Results 101 to 110 of about 56,006 (286)

The impact of future sea-level rise on the tides

open access: yes, 2014
Tides (along with mean sea-level and surges) are a key component in coastal extreme water levels. This investigation begins by assessing the effect of future sea-level rise (SLR) on the tides of the northwest European Continental Shelf.
Pickering, Mark
core  

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar   +3 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Accounting for choice of measurement scale in extreme value modeling [PDF]

open access: yes, 2010
We investigate the effect that the choice of measurement scale has upon inference and extrapolation in extreme value analysis. Separate analyses of variables from a single process on scales which are linked by a nonlinear transformation may lead to ...
J. A. Tawn   +8 more
core   +1 more source

Evaluation of sea level rise and associated responses in Hangzhou Bay from 1978 to 2017

open access: yesAdvances in Climate Change Research, 2018
The mean sea level, extreme sea level, and astronomical tide in Hangzhou Bay were analyzed using the tide gage data from 1978 to 2017 in Tanxu station, and the effects of rising sea levels on floods were estimated.
Jian-Long Feng   +4 more
doaj   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

Determination of extreme sea levels along the Iberian Atlantic Coast

open access: yes, 2016
Resumo: Extreme sea levels along the Atlantic Iberian coast are determined through the development and application of a numerical model for tides and surges, followed by a statistical analysis of the model results.
Rodrigues, M.   +4 more
core   +2 more sources

Assessing the inundation risk resulting from extreme water levels under sea-level rise: a case study of Rongcheng, China

open access: yesGeomatics, Natural Hazards & Risk, 2018
Driven by global climate change, sea-level rise would exacerbate the hazard of extreme water level as a disaster-inducing factor. Based on Representative Concentration Pathway (RCP) 2.6, 4.5, and 8.5, this study explored the inundation risk of extreme ...
Aiqing Feng   +5 more
doaj   +1 more source

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