Results 81 to 90 of about 56,006 (286)
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Time-series of monthly mean steric sea levels
, 2015 This dataset with monthly mean sea levels complements the Global Tide and Surge Reanalysis (GTSR) dataset. The GTSR time-series do not includes variations in mean sea level driven by changes in water mass and water density.
Haigh, I.D. (Ivan), Muis, S. (Sanne)
core +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Extreme sea levels in the English Channel 1900 to 2006
, 2009 Coastal populations are growing at a rapid pace and this is being accompanied by an increased investment in infrastructure at the coastal zone. Combined with this is the concern of enhanced coastal flooding due to rising sea levels and climate change ...
Haigh, Ivan David
core
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
, 2021 International audienceThe estimation of the sea levels with a high return period is crucial for coastal planning and the assessment of coastal flooding risk. Coastal facilities are designed to very low probabilities of failure and hence the design values
Saint Criq, Laurie +3 more
core +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Sea-level change and storm surges in the context of climate change
, 2000 This paper reviews the latest research in New Zealand surrounding the issues of sea-level rise and extreme sea levels in the context of global warming and variability in the Pacific-wide El Nino– Southern Oscillation (ENSO).
Bell, Robert G. +2 more
core
Interpreting century-scale changes in southern North Sea storm surge climate derived from coupled model simulations [PDF]
, 2010 This paper describes numerical experiments using a climate storm surge simulation system for the coast of the United Kingdom with a particular focus on the southern North Sea and the Thames estuary in southeastern England Time series of surges simulated ...
Horsburgh, Kevin +5 more
core +1 more source