Results 61 to 70 of about 56,006 (286)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Wind and Wave Setup Contributions to Extreme Sea Levels at a Tropical High Island: A Stochastic Cyclone Simulation Study for Apia, Samoa

open access: yesJournal of Marine Science and Engineering, 2015
Wind-wave contributions to tropical cyclone (TC)-induced extreme sea levels are known to be significant in areas with narrow littoral zones, particularly at oceanic islands. Despite this, little information exists in many of these locations to assess the
Ron Karl Hoeke   +2 more
doaj   +1 more source

Underestimation of extremes in sea level surge reconstruction

open access: yesScientific Reports
AbstractStatistical models are an alternative to numerical models for reconstructing storm surges at a low computational cost. These models directly link surges to metocean variables, i.e., predictors such as atmospheric pressure, wind and waves. Such reconstructions usually underestimate extreme surges.
Harter, Ludovic   +2 more
openaire   +5 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Statistical models for dependent and non-stationary extreme events [PDF]

open access: yes, 2007
Extreme value methods are used in a wide range of applications, for example they may be used for modelling wave heights and river levels in hydrology, wind speeds in structural engineering and share price return levels in economics.
Eastoe, Emma F, Eastoe, Emma F.
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Global Tide and Surge Reanalysis (GTSR)

open access: yes, 2013
GTSR (Global Tide and Surge Reanalysis) is the first global reanalysis of storm surges and extreme sea levels based on hydrodynamic modelling. GTSR covers the entire world's coastline and provides estimates of extreme sea levels with a 1-in-100 year ...
Muis, S. (Sanne)
core   +1 more source

Resilience to Sea Level Extremes, Trondheim

open access: yes, 2023
Improving the resilience of human settlements is required by United Nations Sustainable Development Goals (UN SDG's) 11 and 13. As a coastal country, the resilience to sea level extremes is of great importance to Norway. Previous studies have focused on national or global level risk, however sea level extremes are highly localized and the understanding
openaire   +2 more sources

The Effect of Non-Stationarity on Extreme Sea-Level Estimation

open access: yesJournal of the Royal Statistical Society Series C: Applied Statistics, 1999
SUMMARY The sea-level is the composition of astronomical tidal and meteorological surge processes. It exhibits temporal non-stationarity due to a combination of long-term trend in the mean level, the deterministic tidal component, surge seasonality and interactions between the tide and surge.
Dixon, M. J., Tawn, J. A.
openaire   +2 more sources

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