Results 71 to 80 of about 662,489 (267)

The influence of circulation patterns on extreme thermal resources in the growing season and the period of active plant growth in Poland (1951?2006)

open access: yesMeteorologische Zeitschrift, 2013
This paper deals with the problem of circulation patterns on extreme thermal resources during the growing season in Poland. Thermal resources were specified using the sums of surpluses of mean daily air temperature values above the thresholds of 5.0 °C ...
Elwira Żmudzka
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

The transfer theorems for density of extreme values

open access: yesLietuvos Matematikos Rinkinys, 2005
In this paper the transfer theorems for density of minima and maxima of independent identically distributed random variables is proved.
Arvydas Jokimaitis   +1 more
doaj   +1 more source

Stochastic Extreme Wind Speed Modeling and Bayes Estimation under the Inverse Rayleigh Distribution

open access: yesApplied Sciences, 2020
Inverse Rayleigh probability distribution is shown in this paper to constitute a valid model for characterization and estimation of extreme values of wind speed, thus constituting a useful tool of wind power production evaluation and mechanical safety of
Elio Chiodo, Luigi Pio Di Noia
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Testing Conditions and Estimating Parameters in Extreme Value Theory

open access: yesRevstat Statistical Journal, 2019
Extreme Value Theory has been asserting itself as one of the most important statistical theories for the applied sciences providing a solid theoretical basis for deriving statistical models describing extreme or even rare events.
Helena Penalva   +3 more
doaj   +1 more source

Simulation of multivariate extreme values [PDF]

open access: yesProceedings of the 29th conference on Winter simulation - WSC '97, 1997
A comprehensive method for simulation of bivariate extremes is developed. A list of explicit algebraic expressions is given for ready implementation of the methodology. The performance of the methodology is assessed in terms of both its efficiency and the fidelity of the generated numbers to the model that they are assumed to come from.
openaire   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

On a the Test for Homogeneity and Extreme Values

open access: yesThe Annals of Mathematical Statistics, 1952
Let $x_1, x_2, \cdots, x_n$ be positive, identically distributed, independent random variables. It is of some statistical interest to study the distribution of $z_n = (x_1 + x_2 + \cdots + x_n)/\max (x_1, x_2, \cdots, x_n)$. In this paper we give its characteristic function and in a few cases its distribution.
openaire   +3 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

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