Eating problems at age 6 years in a whole population sample of extremely preterm children [PDF]
Aim: The aim of this study was to investigate the prevalence of eating problems and their association with neurological and behavioural disabilities and growth among children born extremely preterm (EPC) at age 6 years. Method: A standard questionnaire
Blissett +37 more
core +2 more sources
A comparison of neonatal outcomes between adolescent and adult mothers in developed countries: A systematic review and meta-analysis [PDF]
Evidence suggests that adolescent pregnancies are at increased risk of adverse neonatal outcomes compared to adult pregnancies; however, there are significant inconsistencies in the literature, particularly in studies conducted in developed countries ...
Marvin-Dowle, K, Soltani, Hora
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Erythrocyte enzyme activities in cord blood of extremely low-birth-weight infants [PDF]
Thesis (Ph. D. in Medical Sciences)--University of Tsukuba, (B), no. 2138, 2005.6.30Joint authors: Akira Hirono ... et alOffprint. Originally published in: American journal of hematology, v.
宮園 弥生
core
The Extremely Low Birth Weight Infant
Major changes in obstetric and neonatal care in the 1990s have led to decrease in mortality and morbidity for very low birth weight (VLBW) infants. However these changes have reached a plateau and that is a cause for concern. There has to be a constant introspection by the health care givers so as to ensure state-of-the-art, evidence based care for ...
openaire +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Initial Metabolic Profiles Are Associated with 7-Day Survival among Infants Born at 22-25 Weeks of Gestation. [PDF]
OBJECTIVE:To evaluate the association between early metabolic profiles combined with infant characteristics and survival past 7 days of age in infants born at 22-25 weeks of gestation. STUDY DESIGN:This nested case-control consisted of 465 singleton live
Anderson, James G +9 more
core +1 more source
Preterm Birth of Extremely Low Birth Weight Infants
Approximately 13% of births in the United States are preterm, defined as occurring before 37 weeks of gestation. This results in more than 540,000 infants a year born prematurely. In other words, one out of every 8 infants is born premature. Even more disturbing is that despite advances in neonatal and perinatal medicine, the incidence of prematurity ...
Jonathan Muraskas +3 more
openaire +2 more sources
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source

