Results 81 to 90 of about 1,168,154 (292)

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Predicting attachment in Portuguese infants born very or extremely preterm: Understanding the roles of infant regulatory behavior, maternal sensitivity, and risk factors [PDF]

A growing body of research shows that early attachment relationships are foundational for children’s later developmental and psychosocial outcomes.However, findings are mixed regarding whether preterm birth predicts later attachment, but insecurity is
Martelo, Inês, Barros, Luísa, Marina Fuertes, Antunes, Sandra, Inês Martelo, Maria João Alves, Marjorie Beeghly, Luísa Barros, Sandra Antunes, Alves, Maria João, Fuertes, Marina, Beeghly, Marjorie   +11 more
core   +1 more source

Association of maternal sleep before and during pregnancy with preterm birth and early infant sleep and temperament

Scientific Reports, 2020
This study aimed to investigate the association of maternal sleep before and during pregnancy with preterm birth, infant sleep and temperament at 1 month of age.
Kazushige Nakahara, Takehiro Michikawa, Seiichi Morokuma, Masanobu Ogawa, Kiyoko Kato, Masafumi Sanefuji, Eiji Shibata, Mayumi Tsuji, Masayuki Shimono, Toshihiro Kawamoto, Shouichi Ohga, Koichi Kusuhara, The Japan Environment and Children’s Study Group   +12 more
doaj   +1 more source

Use of Antihypotensive Therapies in Extremely Preterm Infants [PDF]

Pediatrics, 2013
OBJECTIVE: To investigate the relationships among blood pressure (BP) values, antihypotensive therapies, and in-hospital outcomes to identify a BP threshold below which antihypotensive therapies may be beneficial. METHODS: Prospective observational ...
Beau, Batton, Lei, Li, Nancy S, Newman, Abhik, Das, Kristi L, Watterberg, Bradley A, Yoder, Roger G, Faix, Matthew M, Laughon, Barbara J, Stoll, Krisa P, Van Meurs, Waldemar A, Carlo, Brenda B, Poindexter, Edward F, Bell, Pablo J, Sánchez, Richard A, Ehrenkranz, Ronald N, Goldberg, Abbot R, Laptook, Kathleen A, Kennedy, Ivan D, Frantz, Seetha, Shankaran, Kurt, Schibler, Rosemary D, Higgins, Michele C, Walsh   +22 more
openaire   +2 more sources

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Infants born late/moderately preterm are at increased risk for a positive autism screen at 2 years of age [PDF]

, 2015
Objectives: To assess the prevalence of positive screens using the Modified Checklist for Autism in Toddlers (M-CHAT) questionnaire and follow-up interview in late and moderately preterm (LMPT; 32-36 weeks) infants and term-born controls.
Boyle, Elaine M., Sarah E. Seaton (7604969), Guy, Alexa, Johnson, Samantha J., Alexa Guy (3861196), Marlow, Neil, Bradley N. Manktelow (7604972), Elaine M. Boyle (7627196), Field, David J. (David John), David J. Field (7588490), Samantha Johnson (493518), Smith, Lucy K., N. Marlow (7608419), Lucy K. Smith (7581848), Draper, Elizabeth S., Elizabeth S. Draper (7243004), Seaton, Sarah E., Manktelow, Bradley N.   +17 more
core   +1 more source

Model‐Informed Dose Optimization of Anakinra in Preterm Neonates Implications for Safe and Effective Dosing

Clinical Pharmacology &Therapeutics, EarlyView.
Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li, David K. Metz, Elys Green, Gergely Toldi, Robert Galinsky, Megan Clark, Rebecka Atkinson, Ina Rudloff, Josephine C. Owen, Sara K. DiSimone, Samuel C. Forster, Steven X. Cho, Atif Majid, Graeme R. Polglase, Marcel Favilla, Pramod Pharande, Atul Malhotra, Calum T. Roberts, Scott H. Stansfield, Arvind Sehgal, Kenneth Tan, Alistair J. Gunn, Philip J. Berger, Alex Veldman, Rod W. Hunt, Claudia A. Nold‐Petry, Marcel F. Nold, Carl M. J. Kirkpatrick   +27 more
wiley   +1 more source

Three dimensional optical imaging of blood volume and oxygenation in the neonatal brain [PDF]

, 2006
Optical methods provide a means of monitoring cerebral oxygenation in newborn infants at risk of brain injury. A 32-channel optical imaging system has been developed with the aim of reconstructing three-dimensional images of regional blood volume and ...
Yusof, RM, Meek, JH, Hebden, JC, Austin, T, Branco, G, Gibson, AP, Wyatt, JS, Delpy, DT, Arridge, SR   +8 more
core  

Does angiotensin-1 converting enzyme genotype influence motor or cognitive development after pre-term birth? [PDF]

, 2005
Background Raised activity of the renin-angiotensin system (RAS) may both amplify inflammatory and free radical responses and decrease tissue metabolic efficiency and thus enhance cerebral injury in the preterm infant.
Montgomery, H, Harding, DR, Devadason David, Humphries, S, Whitelaw, A, David Davedason, Marlow Neil, Montgomery Hugh E, Marlow, N, Hugh E Montgomery, Davedason, D, Andrew Whitelaw, Humphries, SE, Neil Marlow, Montgomery, HE, Whitelaw Andrew, Humphries Steve E, Dhamrait Sukhbir, Devadason, D, Dhamrait, S, Steve E Humphries, Harding David R, David R Harding, Sukhbir Dhamrait   +23 more
core   +1 more source