Results 51 to 60 of about 29,130 (214)

Unintended Pregnancies and Breastfeeding Studies during Central Nervous System Drug Development: How Are they Handled, Is There Room for Improvement?

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnant and breastfeeding individuals are routinely excluded from clinical drug development, creating persistent evidence gaps in pharmacology, safety, and dosing. Despite mandatory contraception and pregnancy testing, unintended pregnancies occur, particularly during the development of central nervous system (CNS) medicines used by women of ...
Sam Schoenmakers, Charlotte Bakker, Alexandra Ganev, Florence Butlen‐Ducuing, Corinne S. de Vries   +4 more
wiley   +1 more source

Rising public costs of preterm infant hospitalization in South Korea from a nationwide observational study

Scientific Reports
Despite the decline in the overall birth rate, increasing preterm births and associated medical costs pose a national concern. We analyze hospitalization costs covered by national public insurance for preterm infants. Population-based data, obtained from
Ji Young Lee, Joonsik Park, Myeongjee Lee, Minkyung Han, Sung Min Lim, Jee Yeon Baek, Ji-Man Kang, Min Soo Park, Inkyung Jung, Jong Gyun Ahn   +9 more
doaj   +1 more source

Oxygen supplementation to stabilize preterm infants in the fetal to neonatal transition: no satisfactory answer.

Frontiers in Pediatrics, 2016
Fetal life elapses in a relatively low oxygen environment. Immediately after birth with the initiation of breathing the lung expands and oxygen availability to tissue rises by twofold generating a physiologic oxidative stress. However, both lung anatomy
Isabel eTorres-Cuevas, Maria eCernada, Antonio eNuñez, Javier eEscobar, Julia eKuligowski, Consuelo eChafer-Pericas, MAXIMO eVENTO   +6 more
doaj   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Prevalence and risk factors for postpartum depression and stress among mothers of preterm and low birthweight infants admitted to a neonatal intensive care unit in Accra, Ghana

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 131-137, April 2025.
Abstract To determine the prevalence of postpartum depression (PPD) and postpartum stress (PPS) and identify associated risk factors among mothers of preterm and low birth weight (LBW) infants. We conducted a secondary analysis of data collected from 255 mothers with preterm and LBW infants admitted to the neonatal intensive care unit (NICU) at Korle ...
John Pellegrino, Paddington T. Mundagowa, Kwame Sarfo Sakyi, Prince Gyebi Owusu, Babbel Agbinko‐Djobalar, Leila M. Larson, Mufaro Kanyangarara   +6 more
wiley   +1 more source

Neurosonography: Shaping the future of neuroprotection strategies in extremely preterm infants

Heliyon
This review aims to explore the current application of Cranial Ultrasound Screening (CUS) in the diagnosis and treatment of brain diseases in extremely preterm infants. It also discusses the potential role of emerging ultrasound-derived technologies such
Lukun Tang, Qi Li, Feifan Xiao, Yanyan Gao, Peng Zhang, Guoqiang Cheng, Laishuan Wang, Chunmei Lu, Mengmeng Ge, Liyuan Hu, Tiantian Xiao, Zhaoqing Yin, Kai Yan, Wenhao Zhou   +13 more
doaj   +1 more source

Optimal timing for induction of labor in normotensive women: A retrospective cohort study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 365-371, April 2025.
Abstract Objective Labor induction is offered to reduce the risk of stillbirth at late term (41+0 to 41+6) but earlier induction in normotensive singleton pregnancies is supported by weak evidence. The aim of the present study was to investigate the optimal timing for induction in normotensive women.
Jóhanna Gunnarsdóttir, Emma Marie Swift, Alexander Smárason, Kristjana Einarsdóttir   +3 more
wiley   +1 more source

Prematurity and Epigenetic Regulation of SLC6A4: Longitudinal Insights from Birth to the First Month of Life

Biomedicines
Background/Objectives: Prematurity is a significant global health concern, often associated with neurodevelopmental challenges. Solute Carrier Family 6 Member 4 (SLC6A4), the gene encoding the serotonin transporter, a key component in serotonin reuptake ...
Aline de Araújo Brasil, Leo Travassos Vieira Milone, Paulo Victor Barbosa Eleutério dos Santos, Stephanie Cristina Alves de Oliveira Saide, Vitor Barreto Paravidino, Georgia Chalfun, Letícia Santiago da Silva Ferreira, Mariana Berquó Carneiro Ferreira, Anna Beatriz Muniz Ferreira, Geovanna Barroso de Farias, Jaqueline Rodrigues Robaina, Mariana Barros Genuíno de Oliveira, Maria Clara de Magalhães-Barbosa, Arnaldo Prata-Barbosa, Antonio José Ledo Alves da Cunha   +14 more
doaj   +1 more source

Network meta‐analysis of tocolytics in preterm labor: Establishing an evidence‐based treatment hierarchy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella, Chiara Cassani, Vittoria Morteo, Alessandra Marmiroli, Mattia Dominoni, Arsenio Spinillo   +5 more
wiley   +1 more source

Understanding creatine for neurological health in babies (UNICORN): an observational cohort study

Journal of the International Society of Sports Nutrition
Background Creatine is essential for brain development. UNICORN is an observational study designed to assess creatine levels in preterm infants, examine creatine availability through nutrition in the weeks after preterm birth, and correlate preterm ...
Nhi T. Tran, Mary J. Berry, Melissa Schlegel, Alison Sheppard, Damien L. Callahan, Miranda L. Davies-Tuck, Natalie Holowko, Rod W. Hunt, David W. Walker, Rod J. Snow, Stacey J. Ellery   +10 more
doaj   +1 more source