Results 51 to 60 of about 161,362 (295)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Volúmetro com câmaras comunicantes: apresentação de um protótipo de dimensões reduzidas desenvolvido para a avaliação objetiva do volume de mão Volumeter with communicating chambers: presentation of a prototype with reduced dimensions developed for objective assessment of hand volume

open access: yesJornal Vascular Brasileiro, 2010
A volumetria tradicional por deslocamento de água, que utiliza o princípio do transbordamento de Arquimedes, é considerada o padrão-ouro da avaliação do volume de membros, porém tem seu uso rotineiro prescindido por apresentar uma série de desvantagens ...
Rogério Mendonça de Carvalho   +2 more
doaj   +1 more source

Perioperative chemotherapy with ifosfamide and doxorubicin for high-grade soft tissue sarcomas in the extremities (JCOG0304).

open access: yesJapanese Journal of Clinical Oncology, 2015
OBJECTIVE The efficacy of perioperative chemotherapy for soft tissue sarcomas is controversial and only a few prospective studies of pre-operative chemotherapy for soft tissue sarcomas in the extremities have been reported. We therefore carried out Phase
Kazuhiro Tanaka   +11 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Prospective analysis of extremity gunshot injuries treated in a Nigerian regional trauma center

open access: yesInternational Journal of Medicine and Health Development, 2019
Background: Extremity gunshot injuries are a common cause of morbidity and mortality in our environment. They pose a management challenge because of the complex soft tissue and bony injuries.
Omolade A Lasebikan   +4 more
doaj   +1 more source

Extremes on trees

open access: yesThe Annals of Probability, 2005
Published at http://dx.doi.org/10.1214/009117904000001008 in the Annals of Probability (http://www.imstat.org/aop/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Holger Rootzén   +2 more
openaire   +4 more sources

Unique extremality [PDF]

open access: yesJournal d'Analyse Mathématique, 1998
Let \(R\) be a Riemann surface and \(T(R)\) be the Teichmüller space of \(R\), viewed as the Teichmüller equivalence classes of Beltrami coefficients. The following theorems are proved in this paper: A Beltrami coefficient \(\mu\) is uniquely extremal in its Teichmüller class if, and only if, it is uniquely extremal in its infinitesimal Teichmüller ...
Božin, V.   +3 more
openaire   +5 more sources

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Frontal Tendon Lengthening Plasty for Treatment of Structural Patella Baja

open access: yesArthroscopy Techniques, 2016
Patella baja is a severe complication seen after trauma, prolonged immobilization and surgery. Several surgical methods have been described to proximalize the patella without a change in the patella tendon length.
Valentino F. Bruhin, M.D.   +3 more
doaj  

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