Results 71 to 80 of about 295,939 (313)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Bolustherapy in the general chart of renewal of the lost functions of lower extremities for patients after the diaphyseal fracture of bones of shins [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010 The results of the use of medical clay are considered as a physical therapy mean in the general chart of physical rehabilitation of patients. The existent methods of treatment clay are adapted for the physical rehabilitation of patients.
Zhelezniy A.D.
doaj
TISSUE EXPANDER APPLICATIONS FOR EXTREMITIES [PDF]
, 2013 Introduction: Tissue expanders have been frequently used in reconstructive surgery in order to obtain the necessary skin for the reconstruction of local or distant tissue defects because of their ability to form skin tissues of the same color, same sense
Ince, Bilsev +6 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Approximating real functions which possess nth derivatives of bounded variation and applications
, 2007 The main aim of this paper is to provide an approximation for the function f which possesses continuous derivatives up to the order n − 1 (n ≥ 1) and has the nth derivative of bounded variation, in terms of the chord that connects its end points A = (a,
Dragomir, Sever S., Dragomir, Sever S
core +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Extreme types and extremal models
Annals of Pure and Applied LogicIn the affine fragment of continuous logic, type spaces are compact convex sets. I study some model theoretic properties of extreme types. It is proved that every complete theory $T$ has an extremal model, i.e. a model which realizes only extreme types.
openaire +3 more sources