Results 81 to 90 of about 475,886 (308)

Churg-Strauss Syndrome with Necrosis of Toe Tips [PDF]

open access: yes, 2011
Churg-Strauss syndrome (CSS) is a granulomatous necrotizing vasculitis of unknown etiology associated with bronchial asthma. Despite affecting small to medium-sized vessels, necrosis of the digits due to vasculitis is extremely rare.
Hasegawa, Kenjiro   +9 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Cold shivering activity after unilateral destruction of the vestibular apparatus [PDF]

open access: yes
The bioelectric activity of muscles (flexors and extensors of the forelimbs and hindlimbs) during cold shivering after unilateral destruction of the vestibular apparatus.
Kuzmina, G. I.
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Solitary angiokeratoma of tongue: A case report and review of the literature

open access: yesIndian Journal of Dental Research, 2018
Angiokeratoma is a benign cutaneous lesion of capillaries. It is characterized by large dilated blood vessels in the superficial dermis and hyperkeratosis of extremities.
K Santhosh Kumar   +4 more
doaj   +1 more source

Extreme types and extremal models

open access: yesAnnals of Pure and Applied Logic
In the affine fragment of continuous logic, type spaces are compact convex sets. I study some model theoretic properties of extreme types. It is proved that every complete theory $T$ has an extremal model, i.e. a model which realizes only extreme types.
openaire   +3 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Extremal Properties of Extreme Value Distributions

open access: yesThe Annals of Mathematical Statistics, 1951
The upper and lower bounds for the expectation, the coefficient of variation, and the variance of the largest member of a sample from a symmetric population are discussed. The upper bound for the expectation (Table 1, Fig. 1), the lower bound for the C.V. (Table 2, Fig. 4) and the lower bound for the variance (Fig.
openaire   +3 more sources

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

A study of navigation strategies in spatial-semantic visualizations [PDF]

open access: yes, 2001
Visualisations of abstract data are believed to assist the searcher by providing an overview of the semantic structure of a document collection whereby semantically similar items tend to cluster in space.
Chen, C, Cribbin, T
core  

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