Results 81 to 90 of about 295,939 (313)

Are cold extremities an issue in women’s health? Epidemiological evaluation of cold extremities among Japanese women

open access: yes, 2019
Satoshi Tsuboi,1 Tomosa Mine,2 Yumi Tomioka,3 Saeka Shiraishi,4 Fujiko Fukushima,3 Toshiharu Ikaga4 1Department of Epidemiology, Fukushima Medical University, Fukushima, Japan; 2Department of the Scientific Study of Children, Shokei Gakuin University ...
Shiraishi S   +5 more
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Solitary angiokeratoma of tongue: A case report and review of the literature

open access: yesIndian Journal of Dental Research, 2018
Angiokeratoma is a benign cutaneous lesion of capillaries. It is characterized by large dilated blood vessels in the superficial dermis and hyperkeratosis of extremities.
K Santhosh Kumar   +4 more
doaj   +1 more source

Extremal Properties of Extreme Value Distributions

open access: yesThe Annals of Mathematical Statistics, 1951
The upper and lower bounds for the expectation, the coefficient of variation, and the variance of the largest member of a sample from a symmetric population are discussed. The upper bound for the expectation (Table 1, Fig. 1), the lower bound for the C.V. (Table 2, Fig. 4) and the lower bound for the variance (Fig.
openaire   +3 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Relationship between Extremities in Motor Performance

open access: yes, 2001
The purpose of the study was to examine the relationship between the extremities in different aspects of motor performance, including simple reaction time, choice reaction time, speed of movement, tapping speed, and coordination, i.e., speed of movement/
Heikki V. Vanharanta, Kari J. Kauranen
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Dual-targeted hybrid nanovesicles coordinated bone-muscle regeneration via regulating the DUSP4/p38 MAPK pathway to reverse osteosarcopenia

open access: yesJournal of Nanobiotechnology
Osteosarcopenia (OSP), a degenerative syndrome characterized by concurrent osteoporosis and sarcopenia, exhibits persistently high global prevalence due to aging and disuse, yet lacks targeted therapies.
Benchi Che   +11 more
doaj   +1 more source

The relation between pelvic varicose veins and lower extremity venous insufficiency in women with chronic pelvic pain

open access: yesJournal of the Belgian Society of Radiology, 2012
Purpose: To determine the relation between pelvic varicose veins and lower extremity venous insufficiency in women with chronic pelvic pain. Methods and Materials: This study was done in Yuzuncu Yil University Faculty of Medicine, Department of Radiology,
A Bora   +4 more
doaj   +1 more source

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