Results 51 to 60 of about 2,248 (211)

BN 52021 (a platelet activating factor-receptor antagonist) decreases alveolar macrophage-mediated lung injury in experimental extrinsic allergic alveolitis

open access: yesMediators of Inflammation, 1998
Several lines of research indirectly suggest that platelet activating factor (PAF) may intervene in the pathogenesis of extrinsic allergic alveolitis (EAA).
J-L. Pérez-Arellano   +5 more
doaj   +1 more source

Diagnosis and management of hypersensitivity pneumonitis in adults: A position statement from the Thoracic Society of Australia and New Zealand

open access: yesRespirology, Volume 29, Issue 12, Page 1023-1046, December 2024.
Abstract Hypersensitivity pneumonitis (HP) is an immune‐mediated interstitial lung disease (ILD) relating to specific occupational, environmental or medication exposures. Disease behaviour is influenced by the nature of exposure and the host response, with varying degrees of lung inflammation and fibrosis seen within individuals. The differentiation of
Hayley Barnes   +15 more
wiley   +1 more source

Bidirectional transfer of human cytomegalovirus strains in donor and recipient seropositive lung transplant patients

open access: yesJournal of Medical Virology, Volume 96, Issue 7, July 2024.
Abstract Donor and recipient human cytomegalovirus (HCMV) seropositive (D+R+) lung transplant recipients (LTRs) often harbor multiple strains of HCMV, likely due to transmitted donor (D) strains and reactivated recipient (R) strains. To date, the extent and timely occurrence of each likely source in shaping the post‐transplantation (post‐Tx) strain ...
Büsra Külekci   +9 more
wiley   +1 more source

Autoimmune Hypothyroidism As a Predictor of Mortality in Chronic Hypersensitivity Pneumonitis

open access: yesFrontiers in Medicine, 2017
BackgroundChronic hypersensitivity pneumonitis (CHP) is a fibrotic parenchymal lung disease that occurs when inhalation of environmental antigens leads to immune dysregulation.
Ayodeji Adegunsoye   +9 more
doaj   +1 more source

Fibrotic lung diseases in children

open access: yesPediatric Pulmonology, Volume 59, Issue 5, Page 1165-1174, May 2024.
Abstract In children, pulmonary fibrosis (PF) is an extremely unusual entity that can be observed in some types of interstitial lung disease (ILD). Defining whether ILD is accompanied by PF is important for targeted therapy. Algorithm for the diagnosis of PF in children is not clearly established.
Birce Sunman, Nural Kiper
wiley   +1 more source

PAS staining of bronchoalveolar lavage cells for differential diagnosis of interstital lung disease

open access: yesDiagnostic Pathology, 2009
Bronchoalveolar lavage (BAL) is a useful diagnostic tool in interstitial lunge diseases (ILD). However, differential cell counts are often non specific and immunocytochemistry is time consuming.
Zabel Peter, Hauber Hans P
doaj   +1 more source

Utilizing non‐human primate models to combat recent COVID‐19/SARS‐CoV‐2 and viral infectious disease outbreaks

open access: yesJournal of Medical Primatology, Volume 53, Issue 1, February 2024.
Abstract In recent times, global viral outbreaks and diseases, such as COVID‐19 (SARS‐CoV‐2), Zika (ZIKV), monkeypox (MPOX), Ebola (EBOV), and Marburg (MARV), have been extensively documented. Swiftly deciphering the mechanisms underlying disease pathogenesis and devising vaccines or therapeutic interventions to curtail these outbreaks stand as ...
Taeho Kwon
wiley   +1 more source

Hypersensitivity Pneumonitis: Challenges of a Complex Disease

open access: yesCanadian Respiratory Journal, Volume 2024, Issue 1, 2024.
Hypersensitivity pneumonitis (HP) is a complex interstitial lung disease caused by chronic inhalation of a wide variety of antigens in susceptible and sensitized individuals, commonly associated with an occupational exposure. An impressive number of inciting antigens causing hypersensitivity pneumonitis have been found to cover a wide range of ...
Diana Calaras   +5 more
wiley   +1 more source

Alveolite alérgica extrínseca com expressão imunológica atípica Extrinsic allergic alveolitis with an atypical immune expression

open access: yesRevista Portuguesa de Pneumologia, 2009
A alveolite alérgica extrínseca e a sarcoidose são ambas doenças granulomatosas pulmonares que se caracterizam pela presença de granulomas não necrotizantes. Ambas apresentam alterações típicas no lavado broncoalveolar, com relações CD4/CD8 opostas.
Teresa Costa   +2 more
doaj  

Pulmonary hypertension and lung transplantation waitlist outcomes for hypersensitivity pneumonitis

open access: yesJHLT Open
Background: Hypersensitivity pneumonitis is an interstitial lung disease that can progress to pulmonary hypertension which increases mortality. The European Society of Cardiology recently reduced the diagnostic criteria for precapillary pulmonary ...
Michael J. Nicholson, DO   +2 more
doaj   +1 more source

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