Results 1 to 10 of about 16,287 (133)

Hot Tub Lung: Misdiagnosed Hypersensitivity Pneumonitis Revealing a Mycobacterial Aetiology—A Case Report and Literature Review [PDF]

Respirology Case Reports
Hot tub lung (HTL) is a rare granulomatous pneumonitis caused by inhalational exposure to Mycobacterium avium complex (MAC)‐contaminated hot tub water, with debated pathogenesis encompassing both hypersensitivity and infectious mechanisms.
Fadi Abualhommos, Rahaf Fetyani, Yasmeen Butt, Michael Gotway, Abeer Almajali, Jehad Azar   +5 more
doaj   +3 more sources

Enhanced CCL2–CCR2 signalling promotes recruitment of monocyte-derived macrophages in progressive fibrosing hypersensitivity pneumonitis [PDF]

Respiratory Research
Background Hypersensitivity pneumonitis is characterized by immune dysregulation that often leads to irreversible lung tissue scarring. While elevated monocytes play a key role in idiopathic pulmonary fibrosis, their contribution in progressive fibrotic ...
Rita F. Santos, Catarina Gouveia Cardoso, Ana Pinto, Luciana Oliveira, David Barros Coelho, Melany Gonçalves, André Terras Alexandre, Natália Melo, Patrícia Caetano Mota, Inês Neves, Verónica Cardoso, Susana Guimarães, Conceição Souto Moura, André Carvalho, Luís Flores, Fernando Friões, Pedro Fernandes, Andreia Coelho, Oksana Sokhatska, Marília Beltrão, Luís Delgado, Francisco Vasques-Nóvoa, Adelino Leite Moreira, António Morais, Margarida Saraiva, Helder Novais Bastos   +25 more
doaj   +2 more sources

Concomitant diagnosis of hypersensitivity pneumonitis and localized epithelioid mesothelioma: a rare case report [PDF]

Einstein (São Paulo)
Hypersensitivity pneumonitis is an inflammatory lung disease caused by antigen inhalation after sensitization. Here, we report a rare case of the simultaneous diagnosis of hypersensitivity pneumonitis and epithelioid mesothelioma, a subtype of malignant ...
Simone de Leon Martini, Thiago Krieger Bento da Silva, Bianca Canela Furian, Ana Carolina Storch Klein, Júlia Gabriela Storch Klein, Camila Samrsla Möller, Dâmaris Manfro Pinto Garcia, Guilherme Bohm Ferreira   +7 more
doaj   +2 more sources

Rituximab therapy in patients with treatment-refractory hypersensitivity pneumonitis [PDF]

Scientific Reports
Hypersensitivity pneumonitis (HP) presents with a highly variable clinical course, and traditional treatment includes systemic corticosteroids and strict antigen avoidance.
Yosri Akl, Safy Zahid Kaddah, Shereen Medhat Nassar, Rana Kamal EL Said   +3 more
doaj   +2 more sources

Chronic hypersensitivity pneumonitis is associated with an increased risk of venous thromboembolism: a retrospective cohort study

BMC Pulmonary Medicine, 2021
Background Idiopathic pulmonary fibrosis (IPF) and chronic hypersensitivity pneumonitis share commonalities in pathogenesis shifting haemostasis balance towards the procoagulant and antifibrinolytic activity.
Małgorzata Sobiecka, Monika Szturmowicz, Katarzyna Lewandowska, Agata Kowalik, Ewa Łyżwa, Katarzyna Zimna, Inga Barańska, Lilia Jakubowska, Jan Kuś, Renata Langfort, Witold Tomkowski   +10 more
doaj   +1 more source

Impact of antigen identification on transplant free survival in interstitial lung disease

BMC Pulmonary Medicine, 2023
Introduction Antigen identification impacts diagnosis as well as prognosis in patients with hypersensitivity pneumonitis. An antigen may also be present in other etiologies of interstitial lung disease, however it is unknown whether identification ...
Margaret Kypreos, Kiran Batra, Craig S. Glazer, Traci N. Adams   +3 more
doaj   +1 more source

Fibrotic hypersensitivity pneumonitis

Journal of Advanced Lung Health, 2023
Hypersensitivity pneumonitis (HP), which is otherwise known as extrinsic allergic alveolitis, is a clinical syndrome characterized by diffuse interstitial involvement secondary to exposure to organic antigens.
Ravindran Chetambath, Rameesa Shanavas
doaj   +1 more source

Hypersensitivity pneumonitis onset and severity is regulated by CD103 dendritic cell expression. [PDF]

PLoS ONE, 2017
Pulmonary dendritic cells drive lung responses to foreign antigens, including Saccharopolyspora rectivirgula, a causative agent of hypersensitivity pneumonitis.
Emilie Bernatchez, Anick Langlois, Julyanne Brassard, Nicolas Flamand, David Marsolais, Marie-Renée Blanchet   +5 more
doaj   +1 more source

Cladosporium herbarum Hot-Tub Lung Hypersensitivity Pneumonitis in a Greenhouse Worker

European Journal of Case Reports in Internal Medicine, 2020
Hypersensitivity pneumonitis is understood to be a delayed allergic reaction to the repeated exposure of a usually innocent inhaled agent, causing inflammatory damage to the pulmonary parenchyma, alveoli and terminal bronchioles.
João Pedro Abreu, Joana Esteves, Maria Teresa Boncoraglio, Francisca M Pereira, Carla Costa, Carlos Oliveira   +5 more
doaj   +1 more source

Mesalazine-induced Hypersensitivity Pneumonitis

European Journal of Case Reports in Internal Medicine, 2021
A 57-year-old woman with Crohn's disease (ulcerative proctitis) treated with mesalazine (5-ASA) developed worsening respiratory distress and cough. The lack of response to antibiotics and the results of bronchoalveolar lavage led to the diagnosis of ...
Ana Pereira, Cristina Marques, Teresa Boncoraglio, Joana Esteves, Marinha Silva, Joana Braga, Márcia Ribeiro   +6 more
doaj   +1 more source