Results 121 to 130 of about 121,372 (312)
Animal Models and Experimental Medicine, EarlyView.This graphical abstract summarizes our study in which we established a novel murine model of antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis. Neutrophil recruitment was induced using thioglycolate, followed by timed administration of propylthiouracil and phorbol 12‐myristate 13‐acetate to generate DNase I‐resistant neutrophil ...
Sakiko Masuda +9 more
wiley +1 more source
Lung maneuvers of large amplitudes for probing physiological alterations in mouse models of asthma
Animal Models and Experimental Medicine, EarlyView.Lung maneuvers of small amplitudes, such as the ones performed in oscillometry, are the current gold standard to probe lung mechanics in animals, but they are insensitive to detect baseline physiological alterations in mouse models of asthma. Herein, lung maneuvers of different amplitudes were compared in two mouse models of asthma.
Magali Boucher +4 more
wiley +1 more source
Equine models in translational medicine: A comparative approach to human health
Animal Models and Experimental Medicine, EarlyView.This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh +1 more
wiley +1 more source
The use of vacuum-assisted wound closure to enhance skin graft acceptance in a horse [PDF]
, 2011 A 16-year-old horse was admitted to the clinic of the Department of Surgery and Anesthesiology of Domestic Animals of the Faculty of Veterinary Medicine (Ghent University) for the treatment of a very large, non-healing wound extending over the ...
Jordana-Garcia, Mireia +2 more
core
Animal Models and Experimental Medicine, EarlyView.Four aspiration methods (UV, IN, IT, and OA) were compared, and OA was identified as the most effective delivery technique. A chronic aspiration pneumonia model was then established through repeated OA of food suspension or gastric contents. Integrated analyses, including micro‐CT, histopathology, cytokine profiling, and RNA sequencing, revealed ...
Qianwen Li +4 more
wiley +1 more source
Exploring exudate viscosity: A rheological analysis of wound exudates
Wound Repair and RegenerationAbstractExudate and its viscosity are critical in wound healing. Changes in viscosity can interfere with dressings properties as well as affect the diffusion of immune cells, nutrients, oxygen and bacteria. Current international standards for laboratory testing of wound dressings use a single low‐viscosity solution, named as ‘Test Solution A’, which ...
Gianluca Melotto +2 more
openaire +2 more sources
Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter
Animal Models and Experimental Medicine, EarlyView.Clotrimazole‐loaded PLGA microparticles for intravaginal delivery. Abstract Background Intravaginal drug administration is the most promising strategy for treating vaginal infections to protect women's health, such as vulvovaginal candidiasis (VVC). However, conventional vaginal formulations in the clinic face challenges such as drug leakage and low ...
Yanyu Li +8 more
wiley +1 more source
Guangxi Yike Daxue xuebaoObjective To investigate the components of snake venom and the dynamic changes in protein expression in the exudates of necrotic tissues affected by the Naja atra venom in Guangxi Bama miniature pigs.
XIAO Manqi +7 more
doaj +1 more source
Animal Research and One Health, EarlyView.Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke +9 more
wiley +1 more source