Results 191 to 200 of about 563,019 (246)

No retinopathy after orbital irradiation in patients with thyroid eye disease - a follow up study. [PDF]

Front Endocrinol (Lausanne)
Makhoul S, Aranyosi JK, Csiki E, Urbancsek H, Nagy EB, Erdei A, Fodor M, Kovacs A, Nagy EV, Ujhelyi B.   +9 more
europepmc   +1 more source

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

Advanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su, Meng Yang, Xinfeng Wang, Pa Wu, Zongzhao Zhai   +4 more
wiley   +1 more source

How to interpret low-dose valacyclovir for postherpetic neuralgia in the Zoster Eye Disease Study-a randomized clinical trial. [PDF]

Ann Transl Med
Maleki A, Foster CS.
europepmc   +1 more source

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

Advanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai, Zhuoying Huang, Haonan Lin, Guangrui Ding, Hongjian He, Menna Siddiqui, Meng Zhang, Wilson Wong, Ji‐Xin Cheng   +8 more
wiley   +1 more source

Asymmetric thyroid eye disease. [PDF]

Saudi J Ophthalmol
Rana K, Yong LSS, Garg D, Patel S, Slattery J, Davis G, Chan WO, Selva D.   +7 more
europepmc   +1 more source

Intelligent Thermo‐Self‐Limited Magnetothermia with Heat‐Triggered TERT Silencing for Precision Synergetic Cancer Therapy

Advanced Science, EarlyView.
Telomerase reverse transcriptase (TERT) mRNA induces DNA self‐assembly in cancer cells, boosting the nanoplatform's magnetothermal properties. This magnetothermia then activates the Hsp70 promoter, initiating siRNA synthesis to silence the TERT gene, enhancing cancer treatment.
Liang Zhang, Mingfu Gong, Tao Sun, Shilin Xiao, Yue Zhao, Xiaofeng Yang, Wansu Zhang, Chunyu Zhou, Xu Liu, Dong Zhang   +9 more
wiley   +1 more source

Thyroid-stimulating immunoglobulins as a reliable predictive blood test for thyroid eye disease. [PDF]

Indian J Ophthalmol
Madgar S, Simon GB, Priel A, Sagiv O, Landau-Prat D, Cukierman-Yaffe T, Agmon-Levin N, Shavit R, Smadar L, Zloto O.   +9 more
europepmc   +1 more source

Oral Celastrol Nanomedicine Targeting Intestinal Antigen‐Presenting Cells to Effectively Mitigate Autoimmune Uveitis via Gut‐Retina Axis

Advanced Science, EarlyView.
Oral nanoCEL exhibits effective intestinal targeting of antigen‐presenting cells and restores the Th17/Treg balance in lymph nodes and spleen, ultimately protecting the blood‐retinal barrier by inhibiting peripheral immune cell infiltration and suppressing retinal glial cell activation.
Jinrun Chen, Yuqin Wu, Bofei Xu, Jiabei Hou, Yijing Li, Yuhan Hu, Yutuo Zhu, Wenqiao Zhang, Shuqi Feng, Huanting Jin, Yuchen Cheng, Yuanyuan Jin, Jianhong Zhou, Xingyi Li   +13 more
wiley   +1 more source

Clinical burden of dry eye disease in patients with ocular graft versus host disease. [PDF]

Acad Med Health
Nau CB, Schornack MM, Harthan JS, Fogt JS, Nau AC, Hogan WJ, Shorter ES.   +6 more
europepmc   +1 more source

Secondary dry eye disease in breast cancer patients: a pilot study. [PDF]

Breast
Grasso A, Salerno A, Micera A, Ferraro A, Fornaro E, Esposito G, Coassin M, Altomare V, Di Zazzo A.   +8 more
europepmc   +1 more source