Results 61 to 70 of about 10,983,225 (406)

Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6

Frontiers in Oncology, 2022
ObjectiveUveal melanoma (UM) is the most frequent primary eye cancer in adults with a 50% mortality rate. Characterizing the fundamental signaling pathways that drive UM is of importance for the development of targeted therapy.
Hanqing Wang, Hanqing Wang, Sidi Zhao, Yang Liu, Fengyuan Sun, Fengyuan Sun, Xiaoming Huang, Xiaoming Huang, Tong Wu, Tong Wu   +9 more
doaj   +1 more source

Establishment of noncycloplegic methods for screening myopia and pre-myopia in preschool children

Frontiers in Medicine, 2023
PurposePre-myopia, a non-myopic refractive state, is a key concern for myopia prevention because of its association with a significantly higher risk of myopia in children under 3 years of age.
Yao Yin, Yao Yin, Liping Li, Ting Wang, Senlin Lin, Jia Wang, Hong Wang, Minmin Jiang, Yingyan Ma, Yingyan Ma, Jianfeng Zhu   +10 more
doaj   +1 more source

Genetic testing in Marfan syndrome [PDF]

, 2016
Genetic testing is aiding rapid diagnosis of Marfan syndrome as a basis for management of eye, heart and skeletal disease. The affected patient's mutation can be used as a basis for prenatal or postnatal diagnosis of offspring.
Aragon-Martin, JA, Child, AH, Sage, K
core   +1 more source

DISEASES OF THE EYE

The American Journal of the Medical Sciences, 1909
Includes index. ; Mode of access: Internet.
openaire   +2 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Comparison of expression of molecular markers of peripheral blood lymphocyte activation in patients with small uveal melanoma and healthy controls

Journal of Ophthalmology, 2016
Background: Organ-saving treatment is indicated for patients with small (i.e., ? 3 mm in prominence) uveal melanomas (UM), that being the initial stage of the disease.
S.I. Poliakova, L.N. Velichko, A.V. Bogdanova, I.V. Tsukanova   +3 more
doaj   +1 more source

Eye Disease Information Application Program Using Microsoft Visual Basic 6.0 [PDF]

, 2007
This scientific writing, discusses about how to make an eye disease information usingMicrosoft Visual Basic 6.0. Information can be interpreted as a computer softwarethat has a knowledge base for a particular domain and using inference reasoningresembles
Afiani, D. (Devy), Marzuki, SKom, MMSI Marzuki, SKom, MMSI   +1 more
core  

The spectrum of eye disease in hospitalized adults living with HIV, 1995-2010. [PDF]

, 2014
Eye disease is a well-documented complication of HIV infection. Opportunistic infections generally comprised the majority of pre-antiretroviral therapy (ART) eye complications. With the introduction of ART, opportunistic infections diminished.
Belden, Katherine, Fecarotta, Christopher, Liu, Mengdan, Lontok, Josephine, Miller, Christopher, Perez-Povis, Lorena, Sendecki, Jocelyn, Short, MD, MPH, William   +7 more
core   +2 more sources

IRT5 Probiotics Changes Immune Modulatory Protein Expression in the Extraorbital Lacrimal Glands of an Autoimmune Dry Eye Mouse Model [PDF]

, 2020
PURPOSE. While the association between the gut microbiome and the immune system has been studied in autoimmune disorders, little is known about ocular disease.
Choi, Se Hyun, IM, SIN HYEOG, Kim, Hye Min, Kim, Kwang Pyo, Kim, Mee Kum, Oh, Jae Won, Ryu, Jin Suk   +6 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source