Results 41 to 50 of about 6,026,001 (259)

Psychological Stress and Other Potential Triggers for Recurrences of Herpes Simplex Virus Eye Infections

, 2000
Objective To assess psychological stress and other factors as possible triggers of ocular herpes simplex virus (HSV) recurrences. Design A prospective cohort study nested in a randomized, placebo-controlled, clinical trial.
Herpetic Eye Disease Study Group
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Tuberculous Endophthalmitis With Phthisis Bulbi: A Diagnostic Delay Case Report

Clinical Case Reports
Tuberculous endophthalmitis should be prioritized in differential diagnosis for unexplained endophthalmitis in TB‐endemic regions; early systemic evaluation, timely pars plana vitrectomy, and adjunctive corticosteroids are crucial to prevent phthisis ...
Yanchen Chen, Shengnan Li, Xin Chen, Ningpu Liu, Dongjing Liu   +4 more
doaj   +1 more source

Establishment of noncycloplegic methods for screening myopia and pre-myopia in preschool children

Frontiers in Medicine, 2023
PurposePre-myopia, a non-myopic refractive state, is a key concern for myopia prevention because of its association with a significantly higher risk of myopia in children under 3 years of age.
Yao Yin, Yao Yin, Liping Li, Ting Wang, Senlin Lin, Jia Wang, Hong Wang, Minmin Jiang, Yingyan Ma, Yingyan Ma, Jianfeng Zhu   +10 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

P38 Mitogen-Activated Protein Kinase Protects Against Retinoblastoma Through Regulating USP22/SIRT1/SOST Axis

Frontiers in Oncology, 2022
Retinoblastoma (RB) is the most common intraocular malignancy in children. It has been previously reported that p38 MAPK is related to the pathogenesis of RB. Here we aim at investigating how p38 MAPK affected RB progression through mediating USP22/SIRT1/
Xiaoming Huang, Xiaoming Huang, Jianfeng Wan, Fei Liu, Yang Liu, Lina Wang, Sidi Zhao, Tong Wu, Tong Wu, Fengyuan Sun, Fengyuan Sun   +10 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Clinical Profile, Risk factors and Topographic Characteristics of Keratoconus at a Tertiary Eye Hospital: An Observational Study

Journal of Nepal Medical Association
Introduction: Keratoconus is a non-inflammatory, progressive thinning, most commonly bilateral condition of the cornea involving the central two-thirds of the cornea.
Poonam Shrestha, Bibhuti Thapa, Lazza Singh, Santosh Paudel   +3 more
doaj   +1 more source

Orbitofrontal cholesterol granuloma masquerading as frontal sinus mucoceles: report of two cases

BMC Ophthalmology, 2023
Background Two cases of orbitofrontal cholesterol granuloma masquerading as frontal sinus mucoceles were reported to understand image findings, clinical and histopathologic features of orbitofrontal cholesterol granuloma to improve its diagnosis and ...
Ruimiao Li, Mingyu Ren, Wenjing Wang, Ruixin Li, Lili Zhang, Limin Liu   +5 more
doaj   +1 more source

A Generic Pixel Pitch Calibration Method for Fundus Camera via Automated ROI Extraction

Sensors, 2022
Pixel pitch calibration is an essential step to make the fundus structures in the fundus image quantitatively measurable, which is important for the diagnosis and treatment of many diseases, e.g., diabetes, arteriosclerosis, hereditary optic atrophy, etc.
Tengfei Long, Yi Xu, Haidong Zou, Lina Lu, Tianyi Yuan, Zhou Dong, Jiqun Dong, Xin Ke, Saiguang Ling, Yingyan Ma   +9 more
doaj   +1 more source