Results 31 to 40 of about 6,026,001 (259)

Corneal stromal lenticule transplantation for the treatment of congenital optic disc pit maculopathy : a case report and review

BMC Ophthalmology
Background Congenital optic disc pit (ODP) is a relatively uncommon congenital anomaly of the optic disc, which seriously affects the patient’s vision when combined with optic disc pit maculopathy(ODP-M).
Xiaojuan Zhang, Gang Qiao, Yu Quan, Yukun He, Hui Jiang   +4 more
doaj   +1 more source

Comparing bioelectrical activity of the peripheral retina among myopic patients operated for rhegmatogenous retinal detachment complicated by choroidal detachment

Journal of Ophthalmology, 2018
Background: High myopia is known to be a major risk factor for the development of choroidal detachment (CD) in eyes with rhegmatogenous retinal detachment (RRD).
Alibet Yassine, V.S. Ponomarchuk, G.V. Levytska, N.I. Khramenko   +3 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Rates of referable eye disease in the Scottish National Diabetic Retinopathy Screening Programme [PDF]

, 2014
Aims: Diabetic retinopathy screening aims to detect people at risk of visual loss due to proliferative diabetic retinopathy, but also refers cases of suspected macular oedema (maculopathy).
Lee, N, Scottish Diabetes Research Network (SDRN) Epidemiology group, Wild, S H, Cromie, D T, Colhoun, H. M., Cromie, D. T., Wild, S. H., Morris, A D, Olson, J. A., Philip, Sam, McKnight, J. A., Pearson, D. W. M., Leese, G. P., Morris, Andrew, Lindsay, R.S., Lee, N., Olson, J A, Leese, G P, Wild, S. H.; id_orcid, Looker, H. C., Doig, J, Pearson, D W M, Black, M W, Looker, H C, Doig, J., ?, ?, Nyangoma, S. O., Black, M. W., Lindsay, R. S., Morris, A. D., Nyangoma, S O, Lindsay, R S, Philip, S., Colhoun, H M, McKnight, J A   +34 more
core   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Efficacy of using antibacterial fusidic acid drops in patients with red eye

Journal of Ophthalmology, 2016
Introduction. A red eye includes various etiology diseases of the ocular surface (eyelids, conjunctiva, and cornea) as well as of the vascular tract and lacrimal apparatus, the main feature of which is hyperemia of the conjunctiva of the eye.
G.I.Drozhzhyna, E.V. Sereda, T.B. Gaydamaka, A.L. Molodaia   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Accommodative responses under various viewing conditions in surgical patients with intermittent exotropia: an institutional, retrospective study

BMC Ophthalmology, 2022
Purpose To investigate the difference of spherical equivalent (SE) and pupil diameter in adult patients with intermittent exotropia (IXT) under various viewing conditions before and after surgery.
Ziyi Qi, Linlin Du, Jun Chen, Xun Xu, Xiangui He, Jun Qiang   +5 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6

Frontiers in Oncology, 2022
ObjectiveUveal melanoma (UM) is the most frequent primary eye cancer in adults with a 50% mortality rate. Characterizing the fundamental signaling pathways that drive UM is of importance for the development of targeted therapy.
Hanqing Wang, Hanqing Wang, Sidi Zhao, Yang Liu, Fengyuan Sun, Fengyuan Sun, Xiaoming Huang, Xiaoming Huang, Tong Wu, Tong Wu   +9 more
doaj   +1 more source