Results 21 to 30 of about 3,144,487 (302)

Spontaneous Regression of Choroidal Neovascularization in a Patient with Pattern Dystrophy

Case Reports in Ophthalmological Medicine, 2016
Purpose. To present a case of a patient with pattern dystrophy (PD) associated choroidal neovascularization (CNV) that resolved spontaneously without treatment. Methods.
Anastasios Anastasakis, Flamur Goleni, Gerasimos Livir-Rallatos, Charalampos Livir-Rallatos, Panagiotis Zafirakis, Gerald Allen Fishman   +5 more
doaj   +1 more source

GM2-gangliosidosis, type I (Tay – Sachs disease) in the pediatrician practice

Педиатрическая фармакология, 2021
Background. GM2-gangliosidosis, type I (Tay-Sachs disease) is rare hereditary disease caused by mutations in the HEXA gene encoding the alpha subunit of lysosomal hexosaminidase A.
Natalia V. Zhurkova, Nato D. Vashakmadze, Natella V. Sukhanova, Olga B. Gordeeva, Natalia S. Sergienko, Ekaterina Yu. Zaharova   +5 more
doaj   +1 more source

The Role of Mitophagy in Hereditary Optic Neuropathies. Literature Review

Oftalʹmologiâ, 2021
The role of mitophagy in hereditary optic neuropathies is considering in this review. Mitochondria are intracellular double membrane organelles. They are one of the main components of all eukaryotic cells, they perform many different functions in the ...
N. A. Andreeva, N. L. Sheremet, Yu. K. Murakhovskaya, A. A. Dayal, A. A. Minin   +4 more
doaj   +1 more source

Chapter Twelve - Microbiome manipulation as a target for eye diseases: lessons from humans

, 2023
The gut microbiome has been found to influence diseases of the gastrointestinal tract as well as diseases in remote sites such as the brain, lung, and eye.
Betz, Jason, Galor, Anat, Patel, Veshesh   +2 more
core   +1 more source

Hereditary Optic Neuropathy (Leber\u27s Hereditary Optic Neuropathy)

, 2022
Hereditary Optic Neuropathy - A hereditary optic neuropathy is caused by a genetic variant (or mutation) that causes dysfunction of the neurons (nerve cells) which form the optic nerve.
NANOS
core  

The Use of AAV Vector-based Gene Therapy in the Treatment of Ophthalmic Diseases. Literature Review

Oftalʹmologiâ
Introduction. This review article is devoted to the study of the current state of gene therapy using adeno-associated viruses (AAV) in the treatment of ophthalmic diseases.Objective: The purpose: to evaluate the effectiveness and safety of using gene ...
Z. A. Batyrova, A. Sh. Murtazalieva, J. M. Ramazanova, A. S.‑U. Batchaev   +3 more
doaj   +1 more source

The clinical effectiveness and cost-effectiveness of second-eye cataract surgery: a systematic review and economic evaluation [PDF]

, 2014
Background: Elective cataract surgery is the most commonly performed surgical procedure in the NHS. In bilateral cataracts, the eye with greatest vision impairment from cataract is operated on first.
Jonathan Shepherd, Frampton, Geoff, Geoff Frampton, Petra Harris, Harris, Petra, Andrew Lotery, Keith Cooper, Cooper, Keith, Shepherd, Jonathan, Lotery, Andrew J.   +9 more
core   +1 more source

HEREDITARY DISEASES

, 2023
In this article, diseases caused by the violation of genetic information (hereditary information); It is mainly caused by mutations in chromosomes or genes and is passed down through generations. There is information about mutations occurring as a result
I.I. Mamayusupov, J.M. Kasimov, B.N. Akhunova
core   +1 more source

Spontaneous dislocation of a transparent lens to the anterior chamber: A case report [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2010
Introduction. The causes leading to dislocation of the natural lenses are different involving injuries, hereditary diseases and spontaneous dislocation.
Jovanović Miloš, Stefanović Ivan
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source