Results 71 to 80 of about 951,865 (332)

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

Efficacy of combined use of anti-VEGF (Aflibercept) and lasercoagulation for corneal neovascularisation before keratoplasty

Клиническая практика, 2018
It is known that both pre- and postkeratoplasty neovascularization of the cornea can significantly increase the risk of graft rejection reaction. The article presents preliminary results of the use of a VEGF inhibitor combined with laser coagulation ...
V. R. Mamikonyan, S. A. Malozhen, D. A. Krakhmaleva, S. V. Trufanov, E. A. Pivin   +4 more
doaj   +1 more source

Multifunctional Protein Alpha2-Macroglobulin in Tear Fluid and Blood Serum of Patients with Glaucoma

Oftalʹmologiâ, 2023
Alpha2-macroglobulin (α2-MG) is a multifunctional glycoprotein. Due to the variety of its functions there can be several ways of its involvement in the pathogenesis of the glaucomatous optic neuropathy, including neuroinflammation, amyloid deposition ...
N. B. Chesnokova, T. A. Pavlenko, O. V. Beznos, S. Yu. Petrov, A. M. Bessmertny, O. M. Filippova, O. M. Kalinina, V. I. Kotelin   +7 more
doaj   +1 more source

Development of a Chinese version of the National Eye Institute Visual Function Questionnaire (CHI-VFQ-25) as a tool to study patients with eye diseases in Hong Kong [PDF]

, 2009
Background: To develop a Chinese version of the National Eye Institute Visual Function Questionnaire (CHI-VFQ-25) and to test its reliability and validity in a group of patients with eye diseases in Hong Kong.
Chan, CWS, Lai, WW, Lam, CLK, McGhee, S, Wong, D   +4 more
core   +1 more source

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova, Teresa Fazia, Giovanni Di Caprio, Davide Gentilini, Luisa Bernardinelli, Roberto Bergamaschi   +5 more
wiley   +1 more source

Efficacy and safety of the initial hypotensive treatment with an optimized latanoprost composition

Российский офтальмологический журнал, 2023
Purpose: a comparative study of the efficacy and safety of Latanoprost-Optic, a new composition of excipients and the original latanoprost, in the initial therapy of primary open-angle glaucoma (POAG)Material and methods.
S. Yu. Petrov, E. V. Yani, A. N. Zhuravleva, O. M. Filippova, O. M. Kalinina, L. V. Yakubova, S. M. Kosakyan, L. V. Vasilenkova, I. V. Manukyan   +8 more
doaj   +1 more source

Indigenous practices among Palestinians for healing eye diseases and inflammations [PDF]

, 2005
This paper briefly describes the state health services in general, and eye care in particular for Palestinian Arabs under the British Mandate (1917-1948).
Abu-Rabia, Aref
core   +1 more source

Providing a Realist Perspective on the eyeGENE Database System [PDF]

, 2009
One of the achievements of the eyeGENE Network is a repository of DNA samples of patients with inherited eye diseases and an associated database that tracks key elements of phenotype and genotype information for each patient.
Werner Ceusters
core   +2 more sources

Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo, Riccardo Nistri, Michael Eyre, Cheryl Hemingway, Ming Lim, Thomas Rossor, Asthik Biswas, Kshitij Mankad, Ata Siddiqui, Sniya Sudhakar, Declan Chard, Frederik Barkhof, Arman Eshaghi, Olga Ciccarelli, Yael Hacohen   +14 more
wiley   +1 more source

General and Ophthalmic Manifestations of Herpes Virus Infections

Oftalʹmologiâ, 2016
Herpes viruses are a large group of DNA viruses causing a wide variety of diseases in humans. The exponential growth of medicine in general and advanced achievements of virology in particular authentically verified a wide spectrum of diseases in humans ...
S. V. Sdobnikova, N. A. Тroitskaya, Z. V. Surnina, L. S. Pateyuk   +3 more
doaj   +1 more source