Results 231 to 240 of about 824,906 (299)

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Nanozyme eye drops for retinal barrier penetration and vasculopathy repair. [PDF]

Sci Adv
Xue B, Wang S, Wu T, Wang L, Gao XJ, Cao M, Tang M, Wan Y, Yan X, Jiang W, Jiang B.   +10 more
europepmc   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Prolonged stability of 1% 5-FU eye drops as topical chemotherapy for ocular surface squamous neoplasia. [PDF]

Ocul Surf
Antonietti M, Theotoka D, Djulbegovic MB, Gorman GS, Massey M, Galor A, Karp CL.   +6 more
europepmc   +1 more source

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

Advanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang, Ching Yin Fong, Xin Huang, Bee Luan Khoo   +3 more
wiley   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

Study on the Adsorption Behavior of Preservatives in Multidose Eye Drops and Their Interaction with Packaging Materials. [PDF]

ACS Omega
Guan H, Han X, Sun J, Wang J, Ning B, Sun H, Zhao X.   +6 more
europepmc   +1 more source

Surface Neuronal‐Like Structuring of High‐Strength CFRP for Enhanced Electromagnetic Interference Shielding

Advanced Science, EarlyView.
This study elucidates the microstructural evolution at the material interface of Ni‐plated plain‐weave carbon fiber fabric following vacuum heat treatment at 500°C–900°C under different current densities, as well as the mechanism underlying the synergistic enhancement of electromagnetic shielding and ductility.
Wei Cheng, Ben Jia, Shuhan Xiang, Biao Chen, Yongjun Zhang, Zhuo Liu, Xiaopeng Wan, Heyuan Huang   +7 more
wiley   +1 more source

Effect of 3',4'-Dihydroxyflavonol Eye Drops in a Rat Model of Dispase-Induced Proliferative Vitreoretinopathy. [PDF]

Antioxidants (Basel)
Chan EC, Zeng C, Luu CD, Abbott CJ, Chan NT, Datta KK, Williamson N, Allen PJ, Fan Gaskin JC.   +8 more
europepmc   +1 more source

Nintedanib Eye Drops Inhibit Alkali Burn-Induced Corneal Neovascularization Via RAP1/MEK/ERK Signaling Pathway. [PDF]

Invest Ophthalmol Vis Sci
Li J, Zhang G, Li J, Liu R, Zhu L, Li J, Li Z.   +6 more
europepmc   +1 more source