Results 31 to 40 of about 371,981 (337)

Selenium compound protects corneal epithelium against oxidative stress. [PDF]

PLoS ONE, 2012
The ocular surface is strongly affected by oxidative stress, and anti-oxidative systems are maintained in corneal epithelial cells and tear fluid. Dry eye is recognized as an oxidative stress-induced disease.
Akihiro Higuchi, Hiroyoshi Inoue, Tetsuya Kawakita, Tadashi Ogishima, Kazuo Tsubota   +4 more
doaj   +1 more source

Relevance of Lipid-Based Products in the Management of Dry Eye Disease [PDF]

, 2017
Components of the ocular surface synergistically contribute to maintaining and protecting a smooth refractive layer to facilitate the optimal transmission of light.
Amrane, Mourad, Faure, Marie-Odile, Garrigue, Jean-Sebastien, Holopainen, Juha M., Tong, Louis   +4 more
core   +1 more source

Ophthalmic Outcome in a Belgian Cohort of Cystinosis Patients Treated with a Compounded Preparation of Cysteamine Eye Drops: Retrospective Analysis

Ophthalmology and Therapy, 2019
Introduction Treatment of the anterior segment problems in cystinosis is challenging as oral cysteamine is ineffective in the treatment of corneal problems because of its avascular structure.
Freya Peeters, Catherine Cassiman, Karel Van Keer, Elena Levtchenko, Koenraad Veys, Ingele Casteels   +5 more
doaj   +1 more source

The Effects of 3% Diquafosol Sodium Eye Drops on Tear Function and the Ocular Surface of Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice Treated with Antiglaucoma Eye Medications

Diagnostics, 2020
Anti-glaucoma eye drop treatment often induces dry eyes and can lead to poor medication adherence. This study aimed to investigate the effects of 3% diquafosol sodium eye drops on tear function and the ocular surface epithelium in Sod1−/− ...
Yukari Yagi-Yaguchi, Takashi Kojima, Kazunari Higa, Murat Dogru, Osama MA. Ibrahim, Takahiko Shimizu, Kazuo Tsubota, Jun Shimazaki   +7 more
doaj   +1 more source

Prevention of Dermatologic Side Effects of Bimatoprost 0.03% Topical Therapy [PDF]

, 2006
PURPOSE: To investigate the efficacy of reducing the drop-skin contact to prevent dermatologic side effects of bimatoprost 0.03% topical therapy. DESIGN: Prospective, randomized, single-blinded, internally controlled study.
Centofanti, M, Chimenti, S, Citarella, L, Manni, G, Oddone, F, Tanga, L   +5 more
core   +2 more sources

Patient-reported outcomes measures and patient preferences for minimally invasive glaucoma surgical devices. [PDF]

, 2020
BackgroundMany therapeutic options are available to glaucoma patients. One recent therapeutic option is minimally invasive glaucoma surgical (MIGS) devices. It is unclear how patients view different treatments and which patient-reported outcomes would be
George Spaeth, GH Guyatt, GL Spaeth, Jimmy T. Le, Jimmy T. Le, JT Le, KL Cheung, Kuldev Singh, Malvina Eydelman, MB Eydelman, Michelle E. Tarver, NK Gale, NL Hunter, Qi N. Cui, QN Cui, Ronald D. Hays, T Weldring, Tianjing Li   +17 more
core   +1 more source

In search of disambiguation: development of eye drop bottle sleeves to aid in identification and survey among possible users. A cross-sectional study

São Paulo Medical Journal
BACKGROUND: Considerable numbers of individuals present low vision, blindness, illiteracy and other conditions that could possibly impair their identification of medications, such as eye drops.
Ana Luiza Fontes de Azevedo Costa, Thiago Gonçalves dos Santos Martins, Vagner Rogério dos Santos, Paulo Schor   +3 more
doaj   +1 more source

Current trends among pediatric ophthalmologists to decrease myopia progression—an international perspective [PDF]

, 2018
Purpose To explore what the current worldwide preferred practice patterns of pediatric ophthalmologists are to decrease myopia progression among their patients.
Farzavandi, Sonal K., Gomez-de-Liaño, Rosario, Mezer, Eedy, Sprunger, Derek T., Wygnanski-Jaffe, Tamara, Zloto, Ofira   +5 more
core   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

A case of drug induced lung injury caused by levofloxacin eye drops

Respiratory Medicine Case Reports, 2018
A 78 year-old man, who received levofloxacin eye drops as a perioperative prophylactic antibacterial agent for cataract surgery, developed pyrexia and dyspnea, followed by respiratory failure.
Naoki Hosogaya, Kazuhiro Toida, Hiroshi Ishihara, Kiyotaka Kugiyama   +3 more
doaj   +1 more source