Results 31 to 40 of about 92,053 (259)

The Effects of 3% Diquafosol Sodium Eye Drops on Tear Function and the Ocular Surface of Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice Treated with Antiglaucoma Eye Medications

open access: yesDiagnostics, 2020
Anti-glaucoma eye drop treatment often induces dry eyes and can lead to poor medication adherence. This study aimed to investigate the effects of 3% diquafosol sodium eye drops on tear function and the ocular surface epithelium in Sod1−/− ...
Yukari Yagi-Yaguchi   +7 more
doaj   +1 more source

Finger-Prick Autologous Blood (FAB) Eye Drops for Dry Eye Disease: Single Masked Multi-Centre Randomised Controlled Trial

open access: yes, 2022
Ali Hassan,1,2,* Shafi Balal,1,2,* Erica Cook,3 Hakim-Moulay Dehbi,4 Shahina Pardhan,5 Rupert Bourne,6 Sajjad Ahmad,1,2 Anant Sharma1,2 1Department of External Eye Diseases, Moorfields Eye Hospital, London, UK; 2Department of Ophthalmology, UCL ...
Bourne R   +7 more
core  

Local production of eye drops in the hospital or pharmacy setting: considerations and safety tips. [PDF]

open access: yes, 2023
Most eye medicines for topical use are prepared by pharmaceutical companies using special automated mixing and filling machines. However, some eye drops can be prepared in a pharmacy setting in a hospital. There are several reasons1,
Mohamed-Ahmed, Abeer HA   +1 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Cytotoxicity Evaluation Using in vitro System as a Criteria of Rational Choice of Tear Substitutes

open access: yesOftalʹmologiâ, 2018
Purpose: to evaluate the cytotoxic effect of a wide range of lubricant eye drops on the epithelial cells of the cornea in vitro.Materials and methods. The objects of the study were 11 moisture eye drops with various preservatives and 9 moisture eye drops
O. I. Aleksandrova   +4 more
doaj   +1 more source

Local Ugandan Production of Stable 0.2% Chlorhexidine Eye Drops. [PDF]

open access: yes, 2023
PURPOSE: The purpose of this study was to develop a protocol to prepare buffered chlorhexidine (CHX) eye drops (0.2% w/v) in the United Kingdom that can be reproduced at a production facility in Uganda.
Arunga, Simon   +12 more
core   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Dexamethasone/povidone eye drops versus artificial tears for treatment of presumed viral conjunctivitis: a randomized clinical trial

open access: yes, 2020
To determine whether topical dexamethasone 0.1%/povidone-iodine 0.4% reduces the duration of presumed viral conjunctivitis better than artificial tears and whether the treatment relieves the symptoms of this disease.
Fernandes Felix, Joao Paulo   +8 more
core   +2 more sources

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