Results 61 to 70 of about 381,169 (335)

Adherence, compliance, persistence and concordance in the management of glaucoma, Part I [PDF]

open access: yes, 2012
Adherence is laden with difficulties in relation to the management of glaucoma. Perhaps a significant issue associated with a lack of the aforementioned is associated with the patient's failure to recognize there is a need to administer their eye drops ...
Cox, C. L.
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Expert consensus on the preparation and use of temporarily compounded eye drops for eye infectious diseases

open access: yesYanke Xuebao
Commercial eye drops fail to fully meet the therapeutic requirements for infectious ocular diseases. When treating certain infectious ocular diseases where existing ophthalmic preparations are inadequate, extemporaneously prepared eye drops become ...
Ophthalmic Pharmacy Expert Committee of Guangdong Pharmaceutical Association
doaj   +1 more source

Neurotrophic factors and corneal nerve regeneration [PDF]

open access: yes, 2017
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Lambiase, Alessandro, Sacchetti, Marta
core   +2 more sources

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

Safety of intracameral injection of levofloxacin 0.5% eye drops single dose 0.6 ml preservative free on rabbit eye [version 1; peer review: 2 approved]

open access: yesF1000Research, 2023
Background: This was an experimental, parallel, and randomized study to evaluate the safety of single intracameral injection of 0.6 ml 0.5% preservative-free levofloxacin eye drops on rabbit eye. Methods: In total, 24 eyes of 12 New Zealand white rabbits
Baltazar B. Bisara   +4 more
doaj   +1 more source

Staining and peeling of the internal limiting membrane using a fluorescent dye (Rhodamine 6 G) [PDF]

open access: yes, 2008
Aim: To assess whether low concentrations of a fluorescent dye such as Rhodamine 6G would help the unaided human eye visualise the vitreous and the internal limiting membrane (ILM) under standard halogen illumination.Material/methods: The UV/Vis ...
Haritoglou, Christos   +6 more
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

The Effect of Buddleja officinalis Maxim Eye Drops on Morphology and Apoptosis in Lacrimal Gland of Experimental Dry Eye Rabbit Model

open access: yesJournal of Ophthalmology, 2019
The purpose of this study was to investigate the effects of Buddleja officinalis Maxim eye drops on morphology and apoptosis in lacrimal glands of the experimental dry eye rabbit model.
Genyan Qin   +6 more
doaj   +1 more source

Tacrolimus Loaded Cationic Liposomes for Dry Eye Treatment

open access: yesFrontiers in Pharmacology, 2022
Eye drops are ophthalmic formulations routinely used to treat dry eye. However, the low ocular bioavailability is an obvious drawback of eye drops owing to short ocular retention time and weak permeability of the cornea.
Xiang Chen   +8 more
doaj   +1 more source

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