Results 51 to 60 of about 23,372 (299)
ニサンカ タンソ コテイ ノ タメ ノ ヒカリ ユウキ ハンノウ システム ニ カンスル ケンキュウ [PDF]
, 2000 Planarians can propagate asexually by fission and successive regeneration. During head regeneration, they again form a new pair of eyes, and sometimes supernumerary eyes. The positions of normal and supernumerary eyes and their regeneration abilities are
Fumie Sakai +3 more
core +2 more sources
ENUCLEATION OF EYES POSSIBLY CONTAINING MALIGNANCIES [PDF]
British Journal of Ophthalmology, 1963 THE difficulties of the differential diagnosis between haematomata under the retinal pigment epithelium, degenerative diseases of the macula, and malignant melanomata of the choroid have often been pointed out (Reese and Jones, 1961). These problems have troubled many an eye surgeon and their solution will not be discussed here, but a modification of ...
openaire +3 more sources
Advanced Science, EarlyView.This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren +11 more
wiley +1 more source
Measurement of outflow facility using iPerfusion [PDF]
, 2016 Elevated intraocular pressure (IOP) is the predominant risk factor for glaucoma, and reducing IOP is the only successful strategy to prevent further glaucomatous vision loss.
Bertrand, J +4 more
core +3 more sources
SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy
Advanced Science, EarlyView.During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong +9 more
wiley +1 more source
Annals of General Psychiatry, 2006 Self-enucleation or oedipism is a term used to describe self-inflicted enucleation. It is a rare form of self-mutilation, found mainly in acutely psychotic patients.
Tatarelli Roberto +3 more
doaj +1 more source
Advanced Science, EarlyView.Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing +4 more
wiley +1 more source
Clinicopathological Review of 547 Bulbar Enucleations in Hungary (2006–2017)
Journal of Ophthalmology, 2019 Purpose. To analyse current clinicopathological enucleation indications in a large third-referral centre in a developed country (Hungary) over a period of 12 years. Methods. Retrospective review was performed on 547 enucleated eyes of 543 patients (48.6%
Gábor Tóth +10 more
doaj +1 more source
Combined chemotherapy and intra-arterial chemotherapy of retinoblastoma [PDF]
, 2013 PurposeRetinoblastoma (RB) is the most common primary malignant intraocular tumor in children. Although systemic chemotherapy has been the primary treatment, intra-arterial chemotherapy (IAC) represents a new treatment option.
Abramson +26 more
core +1 more source
Advanced Science, EarlyView.Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang +9 more
wiley +1 more source