Results 51 to 60 of about 23,474 (275)
Combined chemotherapy and intra-arterial chemotherapy of retinoblastoma [PDF]
, 2013 PurposeRetinoblastoma (RB) is the most common primary malignant intraocular tumor in children. Although systemic chemotherapy has been the primary treatment, intra-arterial chemotherapy (IAC) represents a new treatment option.
Abramson +26 more
core +1 more source
ENUCLEATION OF EYES POSSIBLY CONTAINING MALIGNANCIES [PDF]
British Journal of Ophthalmology, 1963 THE difficulties of the differential diagnosis between haematomata under the retinal pigment epithelium, degenerative diseases of the macula, and malignant melanomata of the choroid have often been pointed out (Reese and Jones, 1961). These problems have troubled many an eye surgeon and their solution will not be discussed here, but a modification of ...
openaire +3 more sources
SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy
Advanced Science, EarlyView.During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong +9 more
wiley +1 more source
A modified method of evisceration of a subatrophic eyeball
Российский офтальмологический журнал, 2020 The purpose is to develop a new method of evisceration of the eyeball in II–III degree subatrophies and assess its effectiveness. Material and methods. 172 patients with blind or incurable eyes who underwent one of the three operations: eye evisceration ...
I. A. Filatova +2 more
doaj +1 more source
Postenucleation adjuvant chemotherapy with vincristine, etoposide, and carboplatin for the treatment of high-risk retinoblastoma. [PDF]
, 2011 BACKGROUND: Analysis of 52 eyes with high-risk retinoblastoma managed with postenucleation adjuvant chemotherapy using vincristine sulfate, etoposide phosphate, and carboplatin showed no evidence of systemic metastasis in any case during a mean (range ...
Eagle, Ralph C +5 more
core +2 more sources
Advanced Science, EarlyView.Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing +4 more
wiley +1 more source
Clinical features and survival among children with retinoblastoma in Uganda [PDF]
, 2015 AIMS: To characterise the clinical features, treatment and outcome of children diagnosed with retinoblastoma in Uganda. METHODS: The study comprised a 6-year nationwide enrolment with follow-up.
Waddell, Keith M +7 more
core +4 more sources
Advanced Science, EarlyView.Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang +9 more
wiley +1 more source
Annals of General Psychiatry, 2006 Self-enucleation or oedipism is a term used to describe self-inflicted enucleation. It is a rare form of self-mutilation, found mainly in acutely psychotic patients.
Tatarelli Roberto +3 more
doaj +1 more source
Advanced Science, EarlyView.A tailored bio‐targeted catalytic strategy based on a bacteria‐specific artificial biocatalyst (MoS2/Fe@mercaptophenylboronic acid@hyaluronic acid, MFBH) is proposed for treating bacterial endophthalmitis. This strategy exhibits high‐efficiency peptidoglycan‐targeted bactericidal efficacy in vivo following a single intravitreal injection of an ...
Caixia Sun +9 more
wiley +1 more source