Results 81 to 90 of about 24,596 (311)

Secretory autophagy and epithelial‐to‐mesenchymal transition in cadaveric AMD samples: Novel pathways in disease progression

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine the presence of secretory autophagy and epithelial–mesenchymal transition (EMT) in the macular retinal pigment epithelium (RPE) of human cadaver eyes with different forms of age‐related macular degeneration (AMD). Methods Human cadaver macula samples representing dry and wet AMD, as well as age‐matched controls, were ...
Iswariyaraja Sridevi Gurubaran, Ali Koskela, Hanna Heloterä, Kai Kaarniranta   +3 more
wiley   +1 more source

Reduction of severe visual loss and complications following intra-arterial chemotherapy (IAC) for refractory retinoblastoma. [PDF]

, 2017
BACKGROUND: Intra-arterial chemotherapy (IAC) for retinoblastoma has been documented as causing visual loss and ocular motility problems. A lack of safety data has precluded its acceptance in all centres.
Duncan, C, Herod, J, Liasis, A, Naeem, Z, Reddy, MA, Rennie, A, Robertson, F, Sagoo, M, Thompson, DA   +8 more
core   +1 more source

Tumour progression shows decrease in PD‐L1 expression in matched metastases/primary uveal melanomas

Acta Ophthalmologica, EarlyView.
Abstract Purpose Immune checkpoint inhibitors (ICI) have revolutionised the treatment of several malignancies. However, the results of ICI therapy remain unsatisfactory in metastatic uveal melanoma (UM). We analysed the expression of PD1, PD‐L1, T‐cell and macrophage markers in a set of matched primary and metastatic UM in an attempt to better ...
Maria Chiara Gelmi, Gulçin Gezgin, Ellen Kapiteijn, T. H. Khanh Vu, Martine J. Jager, Robert M. Verdijk   +5 more
wiley   +1 more source

Pharmacologic Manipulation of Conventional Outflow Facility in Ex Vivo Mouse Eyes [PDF]

, 2012
PURPOSE. Mouse models are useful for glaucoma research, but it is unclear whether intraocular pressure (IOP) regulation in mice operates through mechanisms similar to those in humans.
Bertrand, J, Boussommier-Calleja, A, Ethier, CR, Overby, DR, Stamer, WD, Woodward, DF   +5 more
core   +1 more source

Reproducibility in the identification of retinal positions on serial fundus photographs: Theory and limitations

Acta Ophthalmologica, EarlyView.
Abstract Background Imaging of the retina is accompanied by distortions so that positions in fundus photographs cannot be linearly translated to positions in the retinal fundus. The purpose of this study was to describe an algorithm and evaluate its reproducibility in identifying points on the retina from their representation on serial fundus ...
Toke Bek, Giovanni Ometto
wiley   +1 more source

Microbial keratitis-induced endophthalmitis: incidence, symptoms, therapy, visual prognosis and outcomes [PDF]

, 2018
Background: To evaluate symptoms, therapies and outcomes in rare microbial keratitis-induced endophthalmitis. Methods: Retrospective study with 11 patients treated between 2009 and 2014.
Feucht, Nikolaus, Khoramnia, Ramin, Loos, Daria, Mayer, Christian, Reznicek, Lukas, Tandogan, Tamer, Zapp, Daniel   +6 more
core   +1 more source

Small lymphocytic lymphoma in true trilineage hematopoietic tissue within heterotopic ossification in an enucleated blind painful eye: a case report

Journal of Medical Case Reports, 2020
Background The finding of hematological malignancies within bone marrow in heterotopic ossification has been reported only a handful of times previously in the literature.
Alfredo Borgia, Sofia Manara, Monica Balzarotti, Paolo Vinciguerra, Alessandra Di Maria   +4 more
doaj   +1 more source

Metastatic potential of small posterior uveal melanomas

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the prevalence of aggressive traits in small posterior uveal melanomas (UM). Methods This retrospective, multicentre cohort study included 804 patients with small posterior UM (≤9 mm in largest basal diameter, ≤3 mm in thickness) from centres in the UK, Germany, and Sweden.
Gustav Stålhammar, Helen Kalirai, Sarah E. Coupland, Salvatore Grisanti, Svenja Rebecca Sonntag, Ayseguel Tura, Antonio Eleuteri, Rumana N. Hussain, Heinrich Heimann, Hannah Coudé Adam   +9 more
wiley   +1 more source

Axial length, myopia progression, and myopic maculopathy in Stickler syndrome

Acta Ophthalmologica, EarlyView.
Abstract Purpose We lack knowledge on the potentially progressive nature of and the prevalence of complications to myopia as a characteristic trait of Stickler syndrome. Methods This cross‐sectional study combines ophthalmic examination and medical record data on Danish patients with genetically confirmed Stickler syndrome type 1 (COL2A1) and type 2 ...
Kirstine B. Boysen, Mette Bertelsen, Nanna D. Rendtorff, Stense Farholt, Line Kessel   +4 more
wiley   +1 more source

Causes and Results of Eye Removal Surgery in Yazd, Iran [PDF]

International Journal of Travel Medicine and Global Health, 2014
Introduction: Removing eyes has different indications. We surveyed the causes and results of eye removal surgery in Yazd, Iran. Methods: We retrospectively reviewed the profile of 102 patients who had underwent eye removal surgery for any reason in the ...
Nasim Oveisi, Tohid Emami Meybodi, Mohammad Reza Besharati, Mohammad Reza Shoja, Farkhonde Khaleghi Dehshiri, Elahe Abbasi Shavazi, Sajad Besharati   +6 more
doaj