Results 171 to 180 of about 31,732 (283)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter‐compatible endovascular electroencephalogram electrode: A clinical feasibility trial

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki   +9 more
wiley   +1 more source

Surmounting Recalcitrant Airway Inflammatory Disorders With a Multi‐Targeting Therapeutic Strategy by Tannic Acid‐Modified CuInP2S6 Nanosheets

open access: yesExploration, EarlyView.
Our findings underscore a multi‐targeting strategy for severe airway inflammation that multi‐targeting nanoformulation C‐TA1 markedly attenuated airway inflammation by (1) cfDNA elimination to alleviate neutrophilic/eosinophilic inflammation mediated by the TLR9 pathway, (2) prevention of RONS‐induced tissue injury and inflammatory response, (3 ...
Ming Liu   +10 more
wiley   +1 more source

Posterior fossa penetrating traumatic brain injury from military blast: illustrative case. [PDF]

open access: yesJ Neurosurg Case Lessons
Breton JM   +7 more
europepmc   +1 more source

Real‐time quality and safety monitoring of fruit juice using paper‐based platform

open access: yesFood Biomacromolecules, EarlyView.
Schematic illustration of a paper‐based biosensor for rapid detection of fruit juice spoilage. Abstract Food spoilage and safety concerns still remain critically challenging within the fruit juice industry, especially as conventional detection methods, though precise, are often too time‐consuming, costly, and reliant on centralized laboratories.
Priti Das   +4 more
wiley   +1 more source

Transorbital Penetrating Intracranial Injury by Wooden Foreign Body: A Rare Case Report. [PDF]

open access: yesClin Case Rep
Chaulagain U   +7 more
europepmc   +1 more source

Nonthermal Food Processing Technologies: A Comprehensive Review

open access: yesFuture Postharvest and Food, EarlyView.
The graphical abstract illustrates the shift from traditional thermal food preservation methods to advanced nonthermal technologies. Traditional methods, represented by heating, often compromise the nutritional and sensory quality of foods. In contrast, nonthermal approaches such as high‐pressure processing (HPP), pulsed electric field (PEF ...
Ashok Kumar Yadav   +5 more
wiley   +1 more source

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