Results 181 to 190 of about 360,662 (293)

Correction: Significant increase of firework induced eye injuries in Germany and The Netherlands- are we doing enough to protect minors and bystanders? [PDF]

Graefes Arch Clin Exp Ophthalmol
Gabel-Pfisterer A, Lang SJ, Boehringer D, Agostini H, de Geus LC, de Faber JT, German firework study group.   +6 more
europepmc   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Using Artificial Intelligence ChatGPT to Access Medical Information About Chemical Eye Injuries: Comparative Study. [PDF]

JMIR Form Res
Alharbi LY, Alrashoud RR, Alotaibi BS, Al Dera AM, Alajlan RS, AlHuthail RR, Alessa DI.   +6 more
europepmc   +1 more source

Description of Main Predictors for Taking Sick Leave Associated with Work-Related Eye Injuries in Spain. [PDF]

Int J Environ Res Public Health, 2021
Martín-Prieto S, Alvarez-Peregrina C, Thuissard-Vassallo I, Catalina-Romero C, Calvo-Bonacho E, Villa-Collar C, Sánchez-Tena MÁ.   +6 more
europepmc   +1 more source

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Finite Element Analysis of Ocular Impact Forces and Potential Complications in Pickleball-Related Eye Injuries. [PDF]

Bioengineering (Basel)
Rydz C, Colmenarez JA, Shahraki K, Dong P, Gu L, Suh DW.   +5 more
europepmc   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Significant increase of firework induced eye injuries in Germany and The Netherlands- are we doing enough to protect minors and bystanders? [PDF]

Graefes Arch Clin Exp Ophthalmol
Gabel-Pfisterer A, Lang SJ, Boehringer D, Agostini H, de Geus LC, de Faber JT, German firework study group.   +6 more
europepmc   +1 more source

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source