Validation of the OptiSafe™ eye irritation test. [PDF]
Cutan Ocul Toxicol, 2020 OptiSafe is an in chemico test method that identifies potential eye irritants based on macromolecular damage following test chemical exposure. The OptiSafe protocol includes a prescreen assessment that identifies test chemicals that are outside the applicability domain of the test method and thus determines the optimal procedure.
Choksi N +13 more
europepmc +7 more sources
Eye Irritation Test of Fel Ursi & Bovis Calculus Pharmacopuncture Solutions for Eye Drop
Journal of Pharmacopuncture, 2008 Objective : This study was done to investigate the safety of Fel Ursi & Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods : The eye irritation test of this material was performed according to the
Hyeong-sik Seo
doaj +2 more sources
Unraveling How Membrane Nanostructure Changes Impact the Eye Irritation of Nonionic Alkyl Ethoxylate Surfactants. [PDF]
ACS Appl Mater Interfaces, 2023 Hu X +8 more
europepmc +2 more sources
Acute Toxicity and Dermal and Eye Irritation of the Aqueous and Hydroalcoholic Extracts of the Seeds of “Zapote” Pouteria mammosa (L.) Cronquist [PDF]
The Scientific World Journal, 2015 The common use of Pouteria mammosa (L.) Cronquist, “Mamey or Zapote,” in food and ethnobotanic medicine shows its low or absent toxicity as fruit extracts prepared from seeds.
Carlos M. S. Dutok +7 more
doaj +2 more sources
Eye Irritation Potential of Microglycine and Microglycine-Containing Ointments: An in vitro Study on Reconstructed Human Corneal Epithelium. [PDF]
Clin Ophthalmol, 2020 Ceriotti L +3 more
europepmc +3 more sources
Rabbit Eye Irritation Tests of Pharmaceutical Intermediates [PDF]
Journal of the American College of Toxicology, 1992 Charissa O'Neal +2 more
openalex +4 more sources
Influence of Corneal Staining in Rabbits on the Evaluation of Eye Irritation Test Results
Shiyan dongwu yu bijiao yixue, 2023 Objective To observe the influence of the staining phenomenon after fluorescein sodium staining on eye irritation in normal rabbits. Methods In the experimental rabbit eye irritation test conducted with sodium chloride eye drops, Siwei Zhenceng ...
XU Honghua +6 more
doaj +1 more source
An unexpected cause of eye irritation: a case of zoonotic ocular onchocerciasis. [PDF]
Case Rep Infect Dis, 2013 Biswas A, Yassin MH.
europepmc +3 more sources
Shanghai yufang yixue, 2022 ObjectiveTo establish bovine corneal opacity and permeability （BCOP） test， and determine its predictive ability for the eye irritation evaluation of cosmetics.MethodsA total of ten reference chemicals were selected to establish the BCOP test.
HUO Qian +8 more
doaj +1 more source
Acute and subacute repeated oral toxicity study of fragmented microplastics in Sprague-Dawley rats
Ecotoxicology and Environmental Safety, 2021 Polypropylene (PP) is the second most highly produced plastic worldwide, and its microplastic forms are found in water and food matrices. However, the effects of PP microplastics on human health remain largely unknown.
Jinsik Kim +6 more
doaj +1 more source