Results 101 to 110 of about 101,230 (328)

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Latanoprost with high precision, piezo-print microdose delivery for IOP lowering: clinical results of the PG21 study of 0.4 µg daily microdose. [PDF]

, 2018
Background:Topical high-precision piezo-print delivery of microdoses of latanoprost achieved significant IOP reduction consistent with the eyedropper effect but with a 75% reduced exposure to drugs and preservatives.
Ianchulev, Tsontcho, Kramm, Robert L, Lin, Shan, Pasquale, Louis R, Tsai, James C, Weinreb, Robert N   +5 more
core  

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Safety assessment of cosmetic products, with emphasis on the ocular area: regulatory aspects and validation processes [PDF]

, 2014
Before marketing a cosmetic product, a series of biological assays, such as ocular irritation tests, must be conducted in order to prove that the product is safe.
Cancian, Maythe de Lima, Guerra, Lucas Offenbecker, Hengeltraub, Simone Fanan, Leonardi, Gislaine Ricci, Leonardi, Mauricio Saadi, Mosca, Mariane Martins   +5 more
core   +4 more sources

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

Advanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen, Ioannis Ziogas, Shirina Alsaedi, Mouza Alshehhi, Shahd Almheiri, Adil Rehman, Khulood Al Shehhi, Hani Saleh, Ahsan Khandoker, Charalampos Pitsalidis, Antoun Khawaja, Anna‐Maria Pappa   +11 more
wiley   +1 more source

Do Pesticide Hazards to Human Health and Beneficial Insects Cause or Result from IPM Adoption? Mixed Messages from Farmer Field Schools in Nicaragua [PDF]

This paper analyzes the interaction between farmer training in pest management and effects on acute pesticide poisoning and populations of beneficial insects in Nicaragua.
Labarta, Ricardo A., Swinton, Scott M.
core   +1 more source

ESAC Opinion on the EURL ECVAM Eye Irritation Validation Study (EIVS) on EpiOcular™ EIT and SkinEthic™ HCE and a related Cosmetics Europe study on HPLC/UPLC-spectrophotometry as an alternative endpoint detection system for MTT-formazan [PDF]

, 2016
ESAC, the EURL ECVAM Scientific Advisory Committee, advises EURL ECVAM on scientific issues. Its main role is to conduct independent peer review of validation studies of alternative test methods and to assess their scientific validity for a given purpose.
BORLAK Jürgen, CARMICHAEL Neil, CARNEY Edward, CLEWELL III Harvey, COSTA Lucio, KEJLOVÁ Kristina, KIRKLAND David, KOPP-SCHNEIDER Annette, KRÄTKE Renate, LEHR Claus-Michael, MARUNOUCHI Tohru, MERRILL Jill, NAVAS Jose M, PIERSMA Aldert, RICHMOND Jon, ROGGEN Erwin, SESARDIC Thea   +16 more
core   +1 more source

Influence of the Degree of Substitution of Carboxymethyl Cellulose Binders on the Properties and Performance of Aqueously Processed LiNi0.6Mn0.2Co0.2O2‐Based Positive Electrodes—A Comparative Study

Advanced Energy and Sustainability Research, EarlyView.
Aqueous processing of positive electrodes is a crucial step toward sustainable production of lithium ion batteries. Therein, the individual properties of the binding agent can largely influence processing, the physical electrode properties, and thus, the electrochemical performance and cycle life.
Johanna Kauling, Chirag Vankani, Martin Winter, Markus Börner   +3 more
wiley   +1 more source

The study of irritation and toxicity of Carthami oil aquapuncture solution applied topically to the skin and the eye mucous membrane

Journal of Pharmacopuncture, 2000
Carthami tinctorii Fructus is known for its good effect on diseases such as fracture, menorrhalgia, menoschesis, puerperium aneilema and so on. The study of irritation and toxicity of Carthami oil aquapuncture solution applied topically to the skin and ...
Lim Sa Bi Na , Kang Dong-Chul
doaj   +1 more source

Effectiveness of the spot-on combination of moxidectin and imidacloprid (Advocate®) in the treatment of ocular thelaziosis by Thelazia callipaeda in naturally infected cats [PDF]

, 2019
Background: The present study evaluated the therapeutic effectiveness of moxidectin 1.0% (w/v) and imidacloprid 10% (w/v) (Advocate® spot-on solution for cats, Bayer Animal Health) against natural infections with the eyeworm Thelazia callipaeda in cats ...
Capelli, G., Falsone, L., Lia, R. P., Nazzari, R., Otranto, D., Petry, G., Pollmeier, M. G., Pombi, M., Solari Basano, F.   +8 more
core   +1 more source