Results 81 to 90 of about 7,196,791 (287)

The study of irritation and toxicity of Carthami oil aquapuncture solution applied topically to the skin and the eye mucous membrane

Journal of Pharmacopuncture, 2000
Carthami tinctorii Fructus is known for its good effect on diseases such as fracture, menorrhalgia, menoschesis, puerperium aneilema and so on. The study of irritation and toxicity of Carthami oil aquapuncture solution applied topically to the skin and ...
Lim Sa Bi Na , Kang Dong-Chul
doaj   +1 more source

Interlaboratory assessment of alternatives to the Draize eye irritation test in Germany.

, 1991
A national interlaboratory study to validate two alternative methods to the Draize rabbit's eye test, co-ordinated by ZEBET at the German Federal Health Office (BGA), is described.
Kreuzer, H., Kreiling, R., Steiling, W., Pape, W.J.W., Gerner, I., Kalweit, S., Spengler, J., Miltenburger, H.G., Siegemund, B., Mürmann, P., Spielmann, H., Krauser, K., Moog, R., Wirnsberger, T., Müller, N., Lüpke, N.P., Wiebel, F.J.   +16 more
core   +1 more source

Molecular restrictions for human eye irritation by chemical vapors [PDF]

, 2005
Previous research showed a cut-off along homologous volatile organic compounds (VOCs) in their ability to produce acute human mucosal irritation. The present study sought to specify the particular cut-off homolog for sensory eye irritation in an acetate ...
Abraham, Michael H., Cometto-Muniz, J. Enrique, Cain, William S.   +2 more
core   +1 more source

Impact of Latanoprost Antiglaucoma Eyedrops and Their Excipients on Toxicity and Healing Characteristics in the Ex Vivo Eye Irritation Test System. [PDF]

Ophthalmol Ther, 2023
Panfil C, Chauchat L, Guerin C, Rebika H, Sahyoun M, Schrage N.   +5 more
europepmc   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Innovative PLA or PCL‐Based Ocular Implants Obtained From Tape Casting or Electrospinning for Sustained‐Release Dexamethasone

Journal of Applied Polymer Science, EarlyView.
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski, Henrique Borba Modolon, Ronaldo Silveira, Januara Rodrigues, Tiago Bender Wermuth, Sabrina Arcaro, Oscar R. K. Montedo   +6 more
wiley   +1 more source

Ascorbic acid specifically reduces the misclassification of nonirritating reactive chemicals in the OptiSafe™ macromolecular eye irritation test. [PDF]

Toxicol In Vitro, 2022
Lebrun S, Chavez S, Chan R, Nguyen L, Jester JV.   +4 more
europepmc   +1 more source

Exceptional preservation informs the paleobiology of tapinocephalid dinocephalians

The Anatomical Record, EarlyView.
Abstract The tapinocephalid dinocephalian Moschops is one of the most iconic taxa of the middle Permian, yet its paleobiology remains one of the least well‐known. Here, we address some aspects of paleoneurology and paleobiology of Moschops using CT scanning of four well preserved skulls from the upper Abrahamskraal Formation of South Africa. Two of the
Julien Benoit, Lars Schmitz, Kenneth D. Angielczyk, Luke A. Norton, Andrew D. Bolton, Adam Midzuk, Roger M. H. Smith   +6 more
wiley   +1 more source

Modeling the antioxidant properties of the eye reduces the false-positive rate of a nonanimal eye irritation test (OptiSafe). [PDF]

Toxicol In Vitro, 2021
Lebrun SJ, Chavez S, Chan R, Nguyen L, Jester JV.   +4 more
europepmc   +1 more source

Comparative analysis of cytoarchitectonic and neurochemical aspects of the globus pallidus in the rock cavy (Kerodon rupestris) and the common marmoset (Callithrix jacchus)

The Anatomical Record, EarlyView.
Abstract The globus pallidus (GP), a subcortical structure within the basal ganglia, plays a crucial role in modulating cortico‐subcortical circuits related to motor control and associative/limbic functions. However, the cytoarchitectonic and neurochemical organization of this structure remains poorly characterized in naturally existing wild‐type ...
Lavínnya Yáskara de Aquino Matoso, Yasmin Pinto Fernandes Albuquerque, Karina Maia Paiva, Rodrigo Freire Oliveira, Nelyane Nayara Martins de Santana, Expedito Silva do Nascimento‐Júnior, Rovena Clara G. J. Engelberth, Jeferson de Souza Cavalcante, Adhil Bhagwandin, Paulo Leonardo Araújo de Góis Morais, José Rodolfo Lopes de Paiva Cavalcanti   +10 more
wiley   +1 more source