Results 41 to 50 of about 229,772 (214)

The Experimental Study of Safety and Efficacy in Using Bovis Calculus Pharmacopuncture Solution as Eye Drop

Journal of Pharmacopuncture, 2009
Objectives : This experimental study was performed to investigate the safety and efficacy of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop.
Hyeongsik Seo
doaj   +1 more source

Therapeutic Effects of Topical Application of Lycium barbarum Polysaccharide in a Murine Model of Dry Eye

Frontiers in Medicine, 2022
PurposeTo evaluate the safety and efficacy of Lycium barbarum polysaccharide (LBP) eye drops in a murine model of dry eye disease (DED).MethodsSix- to eight-week-old female C57BL/6 mice were subjected to a combination of desiccating stress (DS) and ...
Danyi Qin, Yingping Deng, Lixiang Wang, Hongbo Yin   +3 more
doaj   +1 more source

Tear ferning test and pathological effects on ocular surface before and after topical cyclosporine in vernal keratoconjunctivitis patients [PDF]

, 2018
Background: Vernal keratoconjunctivitis (VKC) is a rare ocular surface inflammatory disease that affects mainly boys in the first decade of life.
Bianchi, Guia, Del Regno, Paola, Duse, Marzia, Lambiase, Alessandro, Nebbioso, Marcella, Sacchetti, Marta, Zicari, Anna Maria   +6 more
core   +1 more source

Formulation of ophtalmic vitamin A nanoemulsion with Kolliphor® EL as surfactant and transcutol as cosurfactant and hen’s egg test chorioallantoic membrane (HET CAM) irritation test [PDF]

BIO Web of Conferences
Conventional eye drop preparations are the main choice for the treatment of eye disorders; however, they have low penetration and bioavailability. Vitamin A is nonphotostable, lipophilic, and easily degraded in the presence of oxygen. This study aimed to
Fatmawati Fatimah Siti, Saras Sukmaningrum Galuh, Vanda Pertiwi Deasy, Efiana Nuri Ari   +3 more
doaj   +1 more source

Evaluation of Properties of Dexamethasone Eye Drops

European Pharmaceutical Journal, 2023
During the development of medicinal forms (eye drops), it is necessary to consider several parameters, so that the medicine is nonirritating to the eye and, at the same time, has the desired effect.
Matušová D., Gluštíková P., Špaglová M., Krchňák D.   +3 more
doaj   +1 more source

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study [PDF]

, 2019
Background: Dry eye disease (DED) affects more than 14% of the elderly population causing decrease of quality of life, high costs and vision impairment.
Allegretti, M., Ferrari, M., Garhoefer, G., Lambiase, A., Mantelli, F., Sacchetti, M., Schmetterer, L., Schmidl, D.   +7 more
core   +1 more source

Comparative Study to Assess Clinical Efficacy of Leukotriene Receptor Antagonist and Antihistamines in the Treatment of Allergic Rhinitis

Bengal Journal of Otolaryngology and Head Neck Surgery, 2017
Introduction Pharmacologic treatment  options for allergic rhinitis include intranasal corticosteroids, oral and topical antihistamines, decongestants, intranasal cromolyn, intranasal anticholinergics and leukotriene receptor antagonists. The present
Gurpreet Kaur, Rachna Dhingra, Manjinder Singh   +2 more
doaj   +3 more sources

Expansion of the applicability domain for highly volatile substances on the Short Time Exposure test method and the predictive performance in assessing eye irritation potential

Journal of Toxicological Sciences, 2018
The Short Time Exposure (STE) test method is an in vitro method for assessing the eye irritation potential of chemicals and is used to classify the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Category 1 and No Category ...
Takayuki Abo, Takuo Yuki, Rui‐Hua Xu, Daisuke Araki, Yutaka Takahashi, Hitoshi Sakaguchi, Hiroshi Itagaki   +6 more
openalex   +3 more sources

Pro-Secretory Activity and Pharmacology in Rabbits of an Aminophenyl-1,3,5-Triazine CFTR Activator for Dry Eye Disorders. [PDF]

, 2017
PurposePharmacological activation of ocular surface cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels is a potential pro-secretory approach to treat dry eye disorders.
Felix, Christian M, Lee, Sujin, Levin, Marc H, Verkman, Alan S   +3 more
core   +2 more sources

Nanocubosomal based in situ gel loaded with natamycin for ocular fungal diseases: development, optimization, in-vitro, and in-vivo assessment

Drug Delivery, 2021
Natamycin (NT) is a synthetic broad-spectrum antifungal used in eye drops. However, it has low solubility and high molecular weight, limiting its permeation, and generally causes eye discomfort or irritation when administered.
Khaled M. Hosny, Waleed Y. Rizg, Hala M. Alkhalidi, Walaa A. Abualsunun, Rana B. Bakhaidar, Alshaimaa M. Almehmady, Adel F. Alghaith, Sultan Alshehri, Amani M. El Sisi   +8 more
doaj   +1 more source