Results 41 to 50 of about 28,460 (261)

Sorafenib Repurposing for Ophthalmic Delivery by Lipid Nanoparticles: A Preliminary Study

Pharmaceutics, 2021
Uveal melanoma is the second most common melanoma and the most common intraocular malignant tumour of the eye. Among various treatments currently studied, Sorafenib was also proposed as a promising drug, often administered with other compounds in order ...
Angela Bonaccorso, Veronica Pepe, Cristina Zappulla, Cinzia Cimino, Angelo Pricoco, Giovanni Puglisi, Francesco Giuliano, Rosario Pignatello, Claudia Carbone   +8 more
doaj   +1 more source

Flexible Chemiresistive Chitosan‐Glycerol Sensors on Laser‐Induced Graphene Electrodes for Room‐Temperature Ammonia Detection

Advanced Materials Technologies, EarlyView.
Flexible Chitosan‐glycerol sensor integrated with porous laser‐induced graphene (LIG) electrodes enable room‐temperature chemiresistive detection of ammonia (NH3) and proof‐of‐concept detection of fish spoilage. ABSTRACT We report a metal‐free sensor platform combining laser induced graphene (LIG) electrodes with drop‐deposited, glycerol‐plasticized ...
Mintesinot Tamiru Mengistu, Richard Murray, Cara‐Lena Nies, Cathal Larrigy, Martina Piletti, Jahidul Islam, Daniela Iacopino, Eileen Hurley, Michael Nolan, Aidan J. Quinn   +9 more
wiley   +1 more source

Upcycling Compact Discs Into Ultra‐Stable, Flexible, and Stretchable Nanoporous Gold Electrodes for Enhanced Biosensing Performance

Advanced Materials Technologies, EarlyView.
This article highlights the development of robust and high‐performance flexible and stretchable biosensors that maintain long‐term functionality and optimal electrical conductivity under mechanical deformation, utilizing sustainable and cost‐effective manufacturing principles.
Mousa H. Aldosari, Ahyeon Koh
wiley   +1 more source

Development of a Probability-Based In Vitro Eye Irritation Screening Platform

Bioengineering
Traditional eye irritation assessments, which rely on animal models or ex vivo tissues, face limitations due to ethical concerns, costs, and low throughput.
Seep Arora, Anna Goralczyk, Sujana Andra, Soon Yew John Lim, Yi-Chin Toh   +4 more
doaj   +1 more source

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

Advanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino, Phuoc Thien Phan, James Davies, Bibhu Sharma, Tianruo Guo, Chi Cong Nguyen, Nigel H. Lovell, Thanh Nho Do   +7 more
wiley   +1 more source

Evaluation of a novel anti-oxidant Ubiquinol acetate (EnQ10) for its safety by in vitro methods

Heliyon
Background: As an active form of Coenzyme Q10 (CoQ10), Ubiquinol acetate (EnQ10) is a newly developed, chemically stable, and physiologically active novel antioxidant. In addition to its anti-oxidant properties, CoQ10 is a useful cosmetic agent for human
Mohan Cheluru Umesh, K.M. Geetha, Srinivas Seekallu   +2 more
doaj   +1 more source

A Multidirectional Textile Interface for Remote Control Using Dynamic Area‐Based Capacitance Modulation

Advanced Robotics Research, EarlyView.
Here, we present a textile, wearable capacitive interface enabling multidirectional remote control by dynamically modulating electrode overlap and spacing via a freely gliding upper electrode. A forearm‐mounted prototype drives robotic and media tasks with 12–15 ms latency, maintains < 0.8% drift after 500 cycles, and remains stably functional at 90 ...
Cagatay Gumus, Fulya Yenilmez, Kadir Ozlem, Hakan Kestir, Eren Tasdemir, Berkant Bakisli, Gökhan Ince, Ozgur Atalay, Asli Tuncay Atalay   +8 more
wiley   +1 more source

Preparation and Evaluation of Topically Applied Azithromycin Based on Sodium Hyaluronate in Treatment of Conjunctivitis

Pharmaceutics, 2019
Azithromycin (AZI) eye drops containing sodium hyaluronate (SH) were developed to improve the bioavailability of AZI. Interaction between AZI and SH in the AZI-SH formulation was investigated by differential scanning calorimetry, X-ray diffraction, and ...
Qian Chen, Chun Yin, Jiang Ma, Jiasheng Tu, Yan Shen   +4 more
doaj   +1 more source

The effect of ocular rinse volume on surface irritation after povidone-iodine preparation for intravitreal injections: a randomized controlled trial

International Journal of Retina and Vitreous, 2023
Purpose To evaluate whether the volume of wash out rinse after povidone iodine (PI) application for intravitreal injections (IVI) affects patients’ ocular surface irritation.
Farzad Jamshidi, Haoxing D. Jin, Andrew Bruce, Michael Kutteh, Kai Ding, Kamran M. Riaz, Ronald M. Kingsley, Vinay A. Shah   +7 more
doaj   +1 more source

Facile Fabrication of Low‐Impedance, Highly Conformal Epidermal Electrodes Based on Laser‐Induced Graphene–Silver Nanocomposites

Advanced Science, EarlyView.
A facile laser‐induced graphene–silver nanocomposite strategy enables ultrathin epidermal electrodes with low impedance, high conductivity, and excellent mechanical robustness. The porous LIG–Ag conductive network mechanically interlocked with SEBS provides stable, motion‐resistant biopotential monitoring, enabling high‐fidelity ECG, EMG, and EEG ...
Jiuqiang Li, Senhao Zhang, Kai Guo, Donghai Qiu, Juzhong Zhang, Hongbo Yang, Huanyu Cheng   +6 more
wiley   +1 more source