Results 201 to 210 of about 588,576 (300)

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

On‐Chip Silicon‐Based Micro‐Reflector Pixelated with Micro‐Light‐Emitting Diodes for Augmented Reality Projection Displays

open access: yesAdvanced Science, EarlyView.
This paper presents a pixel‐by‐pixel on‐chip silicon‐based micro‐reflector device (SMRD) for µLEDs that enables simultaneous light‐extraction enhancement and directional emission control. The scalable architecture significantly improves forward light utilization and suppresses pixel crosstalk.
Wenzong Lai   +10 more
wiley   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

open access: yesAdvanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin   +15 more
wiley   +1 more source

High‐Order Nonlinear Photonic Crystal with Ordered Structures for Giant Enhancement of Frequency Tripling

open access: yesAdvanced Science, EarlyView.
A meta‐YAG crystal with artificially order/disorder structures was fabricated to realize the efficient third‐harmonic generation at 343 nm with a conversion efficiency of 4.5×10−3, surpassing six orders of magnitude compared to bulk YAG crystal. Moreover, a wide spectral tunability from 331 to 356 nm was also achieved in the meta‐YAG, indicating its ...
Xiaotian Guo   +6 more
wiley   +1 more source

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