Results 81 to 90 of about 1,249,902 (304)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

The influence of centre thickness on miniscleral lens flexure

, 2019
Purpose To examine the influence of centre thickness upon miniscleral lens flexure and the association between the magnitude of in-vivo lens flexure and scleral toricity.
Collins, Michael, Vincent, Stephen, Alonso-Caneiro, David, Kricancic, Henry, Vincent, Stephen J, Kowalski, Louise, Collins, Michael J, Kowalski, Louise P   +7 more
core   +1 more source

Influence of the use of an intraoperative image-guided alignment system on the refractive outcomes in subjects with preoperative astigmatism: a large comparative retrospective study

BMC Ophthalmology
Background The aim of this study is to compare the refractive outcomes in a large cohort with preoperative corneal astigmatism who underwent cataract surgery with toric intraocular lens (IOL) implantation assisted (study group) or no (control group) with
Luke Rebenitsch, Inder Paul Singh, Julie M. Schallhorn   +2 more
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Short-Term Fit Assessment of a Novel Daily Disposable, Toric, Silicone Hydrogel Contact Lens

Clinical Ophthalmology, 2022
Britt Gustafson,1 Susan Whaley,2 Bradley Giedd,3 Stephen Montaquila,4 Brenda Edwards,5 Lakshman N Subbaraman6 1The Eye Doctors Inc, Eden Prairie, MN, USA; 2Tallahassee Eye Center, Tallahassee, FL, USA; 3Maitland Vision Center, Maitland, FL, USA; 4West ...
Gustafson B, Whaley S, Giedd B, Montaquila S, Edwards B, Subbaraman LN   +5 more
doaj  

Saccade Latency and Fixation Stability: Repeatability and Reliability

Journal of Eye Movement Research, 2016
This study aimed to investigate the repeatability and reliability of saccadic latency and fixation stability as a function of sighting-dominance and contact lens wear.
Gro Horgen, Trine Langaas
doaj   +1 more source

3D Printed Photon Shield Assembly for Low‐Noise Visual Stimulation During Two‐Photon Imaging in Mice

Advanced Materials Technologies, EarlyView.
We present the Photon Shield, an open‐hardware system for low‐noise two‐photon calcium imaging during visual stimulation in mice. Combining a 3D‐printed headplate and rail‐mounted shield substantially reduces stray‐light contamination, as quantitatively verified. Functional validation confirms reliable cortical responses. Open design files enable broad
Gergely Katona, Andrea Slézia, András Dávid, Ábel Petik, Dániel Hillier, István Ulbert, Attila Kaszás   +6 more
wiley   +1 more source

Estimating the whole-body effective dose and health risks as well as introducing a new easy method for eye lens dosimetry in interventional cardiology procedures

MethodsX, 2020
This study aimed to introduce a new method for eye lens thermo-luminescent dosimetry and also estimate the dose associated with induced cancer risk due to the ionizing radiation exposure received by physicians and other staff cooperating in ...
Alireza Hatami, Mahmoud Bagheri, Farzaneh Falahati, Amin Banaei, Razzagh Abedi-Firouzjah, Hamed Zamani, Mohammad Kiapour, Farideh Momeni   +7 more
doaj   +1 more source

Laser‐Induced Local De‐Doping in Organic Semiconductors

Advanced Materials Technologies, EarlyView.
The polymer PBTTT‐C14 doped with the small molecule acceptor F4TCNQ is considered as a benchmark material system. Mask‐free, microscale patterning of the doping level via laser‐induced heating and sublimation of dopant molecules is shown. Controlling laser irradiance and swath spacing allows dopant level control with laser‐limited resolution, opening ...
Christian Rainer, Aleksandr Perevedentsev, Daniel Ryklin, Rasmus R. Schröder, Gerardo Hernandez‐Sosa, Uli Lemmer   +5 more
wiley   +1 more source

A preliminary in vivo assessment of higher-order aberrations induced by a silicone hydrogel monofocal contact lens

, 2008
PURPOSE. To evaluate the effect of negatively powered soft contact lenses on ocular higher-order aberrations (HOAs). METHODS. HOA measurements were performed with fixed optical zones of 4.0 and 6.0 mm on 20 eyes of 10 participants before and minutes ...
Sanchez P., Cavanagh H.D., Sanchez A., Awwad S.T., McCulley J.P.   +4 more
core   +1 more source