Results 171 to 180 of about 1,147,289 (383)
Retinoblastoma in a six-year-old girl
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017 Retinoblastoma is a hereditary malignant tumor of the retina in children and is generally diagnosed before the age of 5. This study presents the clinical case of a 6-year-old girl who came to the department of ophthalmology of Malanje Hospital, Angola ...
Elizabeth Ramírez Pérez +1 more
doaj
The Detection of Saccadic Eye Movements and Per-Eye Comparisons using Virtual Reality Eye Tracking Devices [PDF]
arXivEye tracking has been found to be useful in various tasks including diagnostic and screening tools. However, traditional eye trackers had a complicated setup and operated at a higher frequency to measure eye movements. The use of more commonly available eye trackers such as those in head-mounted virtual reality (VR) headsets greatly expands the utility
arxiv
Prioritization and patients' rights: Analysing the effect of a reform in the Norwegian Hospital Sector [PDF]
The right to equal treatment, irrespective of age, gender, ethnicity, socio-economic status and place of resident, is an important principle for several health care systems.
Askildsen, Jan Erik +2 more
core
Advanced Science, EarlyView.Extracellular matrix (ECM) viscoelasticity and spatial confinement regulate cellular processes such as cancer progression, yet their interplay remains poorly understood. By developing fibronectin (FN)‐micropatterned viscoelastic hydrogels mimicking breast cancer mechanics, this study explores breast epithelial cell mechanoresponse to ECM ...
Giuseppe Ciccone +6 more
wiley +1 more source
The molecular genetics of RASopathies: An update on novel disease genes and new disorders
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 425-439, December 2022., 2022 Abstract Enhanced signaling through RAS and the mitogen‐associated protein kinase (MAPK) cascade underlies the RASopathies, a family of clinically related disorders affecting development and growth. In RASopathies, increased RAS‐MAPK signaling can result from the upregulated activity of various RAS GTPases, enhanced function of proteins positively ...
Marco Tartaglia +2 more
wiley +1 more source
Advanced Science, EarlyView.LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su +17 more
wiley +1 more source
Clinical overview on RASopathies
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022 Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley +1 more source
Nanotherapy for Neural Retinal Regeneration
Advanced Science, EarlyView.Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu +11 more
wiley +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 501-509, December 2022., 2022 Abstract Gene variants that dysregulate signaling through the RAS‐MAPK pathway cause cardiofaciocutaneous syndrome (CFCS), a rare multi‐system disorder. Infantile epileptic spasms syndrome (IESS) and other forms of epilepsy are among the most serious complications.
Daniel L. Kenney‐Jung +14 more
wiley +1 more source
Symptomatic primary iris cysts treated with frequency-doubled Nd:YAG laser photocoagulation
Revista Brasileira de OftalmologiaWe report the case of a 31-year-old woman who presented with a nine-month history of blurred vision in her left eye. Slit-lamp examination and optical coherence tomography showed four cystic masses hanging at the pupillary margin of the left eye ...
Juan Carlos Lua da Costa +5 more
doaj +1 more source