Results 251 to 260 of about 1,147,289 (383)

Krüppel‐like factor 4 transcription factor in blood–brain barrier endothelial cells: A potential role in Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei, Chunhua Liu, Jianyu Chen, Yuxiao Yao, Dajiang Qin   +4 more
wiley   +1 more source

Advances in immunomodulation for organ transplantation: The role of the Annexin A1/FPR axis. [PDF]

Clinics (Sao Paulo)
Silva RAD, Lima JVF, Macedo RFLES, Sant'Ana M, Gil CD, Vergara MN.   +5 more
europepmc   +1 more source

Proteomic Profiling of the Large‐Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling

Arthritis &Rheumatology, EarlyView.
Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan, Erin Macdonald‐Dunlop, Lubna Haroon‐Rashid, Louise Sorensen, Natalie Chaddock, Shauna Masters, Andrew Porter, Marta Peverelli, Charis Pericleous, Andrew Hutchings, James Robinson, Taryn Youngstein, Raashid A. Luqmani, Justin C. Mason, Ann W. Morgan, James E. Peters   +15 more
wiley   +1 more source

A growing pigmented iris lesion in a middle-aged white woman. [PDF]

Digit J Ophthalmol
Ohlhausen M, Rishi P.
europepmc   +1 more source

Recurrence Risk in Pediatric Non‐Infectious Uveitis during Adalimumab Tapering: An International Multicenter Retrospective Study

Arthritis &Rheumatology, Accepted Article.
Objectives This study aims to assess the risk of non‐infectious uveitis (NIU) relapse in pediatric patients undergoing Adalimumab (ADA) tapering, evaluating potential predictors of such risk Methods We conducted a multicenter retrospective cohort study involving pediatric NIU patients who underwent ADA tapering due to inactive uveitis. Cox proportional
Achille Marino, Maria Vittoria Cicinelli, Elisabetta Miserocchi, Stefania Costi, Francesco Baldo, Maurizio Virgilio Gattinara, Pierluigi Scandale, Scott D Smith, Debra A Goldstein, Dina Baddar, Terese KA Gerges, Timothy M Janetos, Matilde Ruiz‐Cruz, Kazuichi Maruyama, Massimiliano Serafino, Paola Camicione, Vishali Gupta, Radgonde Amer, Emilio M Dodds, Sebastian Inchauspe, Marion R Munk, Ester Carreño, Soon‐Phaik Chee, Aniruddha Agarwal, Ariel Schlaen, Ramiro A Gómez, Cristobal A. Couto, Moncef Khairallah, Piergiorgio Neri, Cecilia B Chighizola, Roberto F Caporali, Francesco Pichi   +31 more
wiley   +1 more source

Surgical management of an extensive nasal mass in an adolescent: insights from diagnostic imaging and histopathology. [PDF]

J Surg Case Rep
Asteguieta S, Diaz C, Alarcon J, Godinez V.   +3 more
europepmc   +1 more source

Disproportionate adverse event signals of selumetinib in neurofibromatosis type I: insights from FAERS. [PDF]

Front Pharmacol
Li L.
europepmc   +1 more source

Expert Perspectives on a Clinical Challenge: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, Accepted Article.
Systemic vasculitis describes a collection of rare diseases each caused by inflammation of blood vessel walls that can cause severe systemic complications [[3, 4]](#ref‐0003). The pattern of vascular inflammation and resultant damage is frequently variable and may be mimicked, or directly triggered, by infection or malignancy.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

When Seizures Lead to the Incidental Finding of Silicone Oil Migration. [PDF]

Cureus
Ferreira T, Dias A, D Rebelo S, Tornada A.   +3 more
europepmc   +1 more source