This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang +9 more
wiley +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Immunological Interplay at the Ocular Surface of Stevens-Johnson Syndrome, Ocular Cicatricial Pemphigoid, and Ocular Graft Versus Host Disease. [PDF]
Pingali T +7 more
europepmc +1 more source
The Influence of Immunisation against Eye Lens Protein on the Electrophoretie Picture of Blood Plasma and Eye Lens Proteins [PDF]
W.F. Bon, P.C. Nobel
openaire +1 more source
Temporal Interference Stimulation Enhances Neural Regeneration
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti +15 more
wiley +1 more source
<i>Wolbachia</i> uses ankyrin repeats to target specific fly proteins. [PDF]
Hamilton W +5 more
europepmc +1 more source
Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits
Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu +11 more
wiley +1 more source
Neutrophil Extracellular Traps in Dry Eye: A Comprehensive Review of Pathogenic Mechanisms and Implications for Targeted Therapy. [PDF]
Guo X +6 more
europepmc +1 more source
Mechanozyme: An Artificial Enzyme With a Mechanophore Framework
Mechanical destabilization of a G‐quadruplex mechanophore in a DNAzyme markedly boosts its catalytic activity, demonstrating “mechanozymes” as artificial enzymes whose functions are modulated by mechanical stress exerted by ultrasonication. This mechanozyme principle is broadly applicable to control biomolecular activities.
Jiahao Ji +7 more
wiley +1 more source
Multi-organ acute and delayed effects following exposure to neutron radiation. [PDF]
Gasperetti T +15 more
europepmc +1 more source

