Results 1 to 10 of about 7,313 (213)
Heliyon, 2023 The objectives of this study were to develop a sustained-release device for carteolol hydrochloride (CH) and investigate any potential difference in the intraocular distribution of this agent between the transscleral administration of the device and ...
Yoshiko Hashikawa +4 more
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Reduction in Ocular Surface Culture Positivity Following Short-Term Treatment with Liposomal Ozonated Oil Eyedrops [PDF]
Clinics and PracticeBackground/Objectives: The ocular surface is continuously exposed to microorganisms, and disruption of host–microbial balance may lead to infection or postoperative complications. Increasing antimicrobial resistance and biofilm formation have highlighted
Andreea-Talida Tirziu +7 more
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Pharmaceuticals, 2022 The purpose of this study was to evaluate the safety, tolerability, and pharmacokinetics (PKs) of rhEGF eyedrops after the administration of single and multiple doses in healthy subjects.
Hyounggyoon Yoo +8 more
doaj +2 more sources
Autologous platelet-rich plasma eyedrops for severe dry eye disease unresponsive to autologous serum: A prospective single-arm interventional study [PDF]
Therapeutic Advances in OphthalmologyBackground Some patients with dry eye disease (DED) respond sub-optimally to autologous serum (AS) therapy. Platelet-rich plasma (PRP), a blood-derived preparation with higher platelet-derived growth factor concentrations, may benefit patients refractory
Thapakorn Sirirattanasoporn +4 more
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A systematic review with meta-analysis on the efficacy of 0.01% atropine eyedrops in preventing myopia progression in worldwide children’s populations [PDF]
Frontiers in PharmacologyIntroductionAtropine eyedrops have long been used off-label to prevent myopia progression in children, and many clinical trials have been published on this topic in the past 30 years.
Pierluigi Navarra +4 more
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Irrational ophthalmic fixed-dose combinations for dry eye syndrome
Indian Journal of Ophthalmology, 2022 Dry eye syndrome (DES) is a common disorder with rising incidence due to increased use of digital devices. While multiple treatment options are available, some are not efficacious or sometimes even safe for use in DES. This is particularly true for Fixed
Nilima A Kshirsagar +3 more
doaj +1 more source
Pharmaceutics, 2022 Posterior eye diseases, such as age-related macular degeneration and diabetic retinopathy, are difficult to treat due to ineffective drug delivery to affected areas.
Cheng-Han Tsai +7 more
doaj +1 more source
Life, 2023 Purpose: To examine the effectiveness of a standardized combination of intracameral mydriatics and anesthetic (SCIMA) on mydriasis in patients with coexisting diseases such as diabetes mellitus (DM) and pseudoexfoliation syndrome (PXF) during ...
Joanna Katarzyna Dereń-Szumełda +3 more
doaj +1 more source
Formulation Considerations for the Management of Dry Eye Disease
Pharmaceutics, 2021 Dry eye disease (DED) is one of the most common ocular surface disorders characterised by a deficiency in quality and/or quantity of the tear fluid. Due to its multifactorial nature involving several inter-related underlying pathologies, it can rapidly ...
Priyanka Agarwal +2 more
doaj +1 more source
Mucoadhesive Nanoparticles for Drug Delivery to the Anterior Eye
Nanomaterials, 2020 While the use of topical drops for the delivery of drugs to the anterior of the eye is well accepted, it is far from efficient with as little as 5% of the drug instilled on the eye actually reaching the target tissue. The ability to prolong the residence
Nicole Mangiacotte +4 more
doaj +1 more source