Results 181 to 190 of about 233,296 (239)

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

open access: yesAllergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz   +22 more
wiley   +1 more source

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

open access: yesAllergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith   +9 more
wiley   +1 more source

Environmental Changes and Their Effect on the Airway Microbiome: Implications for Airway Diseases

open access: yesAllergy, EarlyView.
ABSTRACT Obstructive airway diseases, including asthma and chronic obstructive pulmonary disease (COPD), represent the two major chronic airway inflammatory diseases. In both conditions, the airways are exposed to a variety of microbial and environmental stimuli.
Georgios Rentzos   +10 more
wiley   +1 more source

Bridging beauty and wellness: examining beauty professionals' comfort in discussing sexual health. [PDF]

open access: yesFront Reprod Health
Villaire S   +7 more
europepmc   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

open access: yesAndrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou   +8 more
wiley   +1 more source

A Quantitative Evaluation of the PowerRef 3 for Measuring Gaze Position. [PDF]

open access: yesOphthalmic Physiol Opt
Haensel JX   +6 more
europepmc   +1 more source

Sperm Head–Tail Coupling Apparatus Diversity and Common Themes Among Species

open access: yesAndrology, EarlyView.
ABSTRACT Background A stable connection between the sperm head (containing the nucleus and acrosome) and tail (containing the axoneme, mitochondrial sheath, and periaxonemal structures) is critical for fertility. This connection is mediated by a series of nuclear, cytoplasmic, and centriole components that make up the head–tail coupling apparatus (HTCA)
Danielle B. Buglak   +2 more
wiley   +1 more source

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