Results 91 to 100 of about 9,166,726 (386)

Transcript Identification Using Arrayed Hydrogels With TrapFISH

Advanced Materials Technologies, EarlyView.
TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse, Zenon Toprakcioglu, Akhila Denduluri‐Marthi, James D. Brenton, Craig J. Thomas, Tuomas P. J. Knowles   +5 more
wiley   +1 more source

Role of corneal nerves in ocular surface homeostasis and disease

Acta ophthalmologica, 2018
Corneal nerves are key components of the physiological system that controls ocular surface homeostasis. The cornea is primarily innervated by the ophthalmic branch of the trigeminal nerves (cranial nerve V), which distend bilaterally from the pons.
M. Labetoulle, C. Baudouin, M. Calonge, J. Merayo-Lloves, K. Boboridis, Y. Akova, P. Aragona, G. Geerling, E. Messmer, J. Benítez-Del-Castillo   +9 more
semanticscholar   +1 more source

Microfluidic Platform with Local Oxygen Sensors Demonstrates That 3D Blood Vessel Networks Exhibit Time‐Dependent Changes in Oxygen Concentrations During Their Formation and Perfusion

Advanced Materials Technologies, EarlyView.
Novel OoC platform with functional vascular networks highlights challenges in oxygenation. This study uses optical oxygen sensors to monitor oxygen during vascular formation, revealing perfusion limitations and highlighting the need for better oxygenation strategies.
Tarek Gensheimer, Stefanie Fuchs, Laura E. de Heus, Kim Vermeul, Torsten Mayr, Andries v.d. Meer   +5 more
wiley   +1 more source

A High‐Throughput AngioPlate Platform with Integrated AngioTEER for Modeling and Monitoring Renal Proximal Tubule Injury

Advanced Materials Technologies, EarlyView.
Renal tubular injury is a major contributor to kidney disease, yet remains poorly understood due to the lack of predictive models. This study presents a high‐throughput 3D renal proximal tubule model on the AngioPlate platform integrated with automated TEER measurements (AngioTEER), enabling real‐time monitoring of drug‐induced nephrotoxicity ...
Shravanthi Rajasekar, Anushree Chakravarty, Kimia Asadi Jozani, Brenda Truong, Matana Hendrickson, Ahmed Attia, Muna Sabouny, Anna Basatskaya, Sergi Clotet‐Freixas, Madeleine Ludlow, Alexander Sotra, Dawn S. Y. Lin, Feng Zhang, Boyang Zhang   +13 more
wiley   +1 more source

Ocular inserts — Advancement in therapy of eye diseases

Journal of Advanced Pharmaceutical Technology & Research, 2010
The ocular insert represents a significant advancement in the therapy of eye disease. Ocular inserts are defined as sterile, thin, multilayered, drug-impregnated, solid or semisolid consistency devices placed into the cul-de-sac or conjuctival sac, whose
A. Kumari, P. Sharma, V. Garg, G. Garg
semanticscholar   +1 more source

Assessment of Eyelid Pressure Using a Novel Pressure Measurement Device in Patients With Moderate-to-Severe Dry Eye Disease [PDF]

, 2022
Jingyi Wang, Jiayu Bao, Wen-xiu Song, Siyuan Li, Yiran Hao, Lei Tian, Ying Jie   +6 more
openalex   +1 more source

Wirelessly Powered Ingestible Capsule for Optical Stimulation of the Gastrointestinal Tract in Rodents

Advanced Materials Technologies, EarlyView.
An ingestible electronic capsule, ICOPS, enables non‐invasive optical gut stimulation in rodents. ICOPS features modular LEDs and optimized power transfer for robust, in vivo functionality. This cleanroom‐free, 3D‐printed platform offers a compact, scalable solution for optogenetically interfacing enteric neural circuits, promising advances in ...
Mohamed Elsherif, Rawan Badr El‐Din, Zhansaya Makhambetova, Heba Naser, Maylis Boitet, Rahul Singh, Keonghwan Oh, Revathi Sukesan, Sohmyung Ha, Khalil B. Ramadi   +9 more
wiley   +1 more source

Operation procedure of eyelid margin cleaning based on eyelid cleaning device

Yanke Xuebao
Blepharitis is a common chronic eye inflammation that mainly affects the skin and mucosa of the eyelid margin. It is characterized by eye irritation symptoms such as dryness, itching, and foreign body sensation, accompanied by clinical manifestations ...
TIAN Bishan, FU Qi, LI Shuping, DENG Yuqing, XIAO Bing, YUAN Jin   +5 more
doaj   +1 more source

Solvent‐Free Mechanocatalytic Reduction of Nitro Compounds with Hydrogen Gas and its Application in the Synthesis of Drugs and their Intermediates

Advanced Synthesis &Catalysis, EarlyView.
A solvent‐free mechanochemical reduction of nitro compounds using hydrogen gas is presented. In addition to enabling the synthesis of a variety of functionalized aniline derivatives, the method has been scaled up to gram quantities, evaluated for trace metal impurities, and applied to the synthesis of pharmaceutical compounds and their precursors.
Samarth Bhatnagar, Michael Felderhoff, Jan‐Hendrik Schöbel   +2 more
wiley   +1 more source

Compact Multichannel Plasmonic Device for Rapid and Versatile Inflammatory Biomarker Analysis

Advanced Sensor Research, EarlyView.
A multichannel plasmonic biosensor has been developed for the simultaneous detection of up to four inflammatory biomarkers relevant to sepsis diagnostics. Its performance has been optimized, and analytical validation has been conducted for the detection in diluted serum, highlighting its potential for clinical applications.
Juliana Fátima Giarola, Patricia Ramirez‐Priego, M.‐Carmen Estevez, Laura M. Lechuga   +3 more
wiley   +1 more source