Results 51 to 60 of about 50,492 (306)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Detection of human papillomaviruses type 16, 18 and 33 in bronchial aspirates of lung carcinoma patients by polymerase chain reaction: a study of 84 cases in Croatia [Određivanje humanog papiloma virusa tipa 16, 18 i 33 u aspiratima bronha pacijenata s karcinomom pluća metodom lančane reakcije polimerazom: istraživanje 84 pacijenta u Hrvatskoj] [PDF]
, 2010 Besides its well-known role in cervical carcinoma, HPV is also suggested to be involved in lung cancer development. A number of authors have been investigating the presence of HPV in histological materials.
Gajović, Srećko +6 more
core
A Comprehensive Review on Dry Eye Disease: Diagnosis, Medical Management, Recent Developments, and Future Challenges [PDF]
, 2015 Dry eye syndrome (DES) or keratoconjunctivitis sicca (KCS) is a common disorder of the tear film caused by decreased tear production or increased evaporation and manifests with a wide variety of signs and symptoms.
Askarkar, S +4 more
core +2 more sources
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Journal of Ocular Diseases and Therapeutics, 2015 Although aging is natural and acceptable process by most people, it has become a major problem with increased life expectancy and socio-cultural levels. The eyelid protects eyes from dryness, environmental exposure and trauma. It is important that the eyelid is to be robust and in the proper position for eye health.
Neslihan Sevimli +3 more
openaire +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
IDCases, 2020 Melioidosis is an infection caused by the Gram-negative bacterium Burkholderia pseudomallei. Melioidosis can affect any organ and result in a broad spectrum of diseases.
Chee Yik Chang
doaj +1 more source
Rare presentations of primary amyloidosis as ptosis: a case report
BMC Ophthalmology, 2022 Background Amyloidosis is a rare, progressive and variable group of diseases characterized by extracellular deposits of amyloid protein in different tissues and organs.
Peng-Hsuan Lee +2 more
doaj +1 more source
Arthritis Care &Research, Accepted Article.Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni +7 more
wiley +1 more source
Dominant BIN1-related centronuclear myopathy (CNM) revealed by lower limb myalgia and moderate CK elevation [PDF]
, 2015 We report a BIN1-related CNM family with unusual clinical phenotype. The proband, a 56-year-old man suffered of lower limbs myalgia since the age of 52.
Antonini, Giovanni +8 more
core +1 more source