Results 141 to 150 of about 6,183 (285)

Intratumoural tigilanol tiglate in the multicentre treatment of equine sarcoids and cutaneous melanomas

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Intralesional chemotherapeutic administration represents an important treatment option for equine cutaneous neoplasia. Tigilanol‐tiglate (TT), a novel molecule extracted from Fontainea picrosperma, an Australian rainforest plant, is registered for intratumoural treatment of canine MCT, leading to rapid oncosis and tumour slough ...
Raphael Labens   +15 more
wiley   +1 more source

Rare classification of a lower eyelid lesion as tubular apocrine adenoma. [PDF]

open access: yesAm J Ophthalmol Case Rep
Sheth NT, Stamey C, Dermarkarian CR.
europepmc   +1 more source

The protease ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25

open access: yesThe FEBS Journal, EarlyView.
Metastatic progression is characterised by extensive remodelling of the extracellular matrix, primarily mediated by secreted proteases, including ADAMTS family members. Rainero and colleagues found that the small GTPase Rab25 promoted the expression of ADAMTS5 in ovarian cancer cells through the activation of the NF‐κB signalling pathway.
Shengnan Yuan   +7 more
wiley   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

open access: yesThe FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický   +22 more
wiley   +1 more source

Calcinosis cutis of the lower legs – hyperphosphatemic familial tumoral calcinosis in a patient with GALNT3 mutation

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
David Ranzinger   +4 more
wiley   +1 more source

A Growing Pink Periorbital Papule in a Middle‐Aged Man: A Clinicopathological Challenge

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT This report describes a case of a 48‐year‐old man who presented with a slowly enlarging lesion on the right lower eyelid that had been present for 8–9 years. The skin biopsy revealed an apocrine carcinoma of the eyelid. We discuss the clinical and histopathological differential diagnosis of apocrine carcinoma, along with treatment ...
Lydia A. Luu, Linglei Ma, Mark Russell
wiley   +1 more source

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