Results 181 to 190 of about 6,183 (285)

The Pathophysiological Functions of Heparanases: From Evolution, Structural and Tissue‐Specific Perspectives

The FASEB Journal, Volume 39, Issue 17, 15 September 2025.
Heparanase 1 (HPSE1) and Heparanase 2 (HPSE2) exhibit opposing expression patterns and functions in pathological contexts, such as cancer. Here, we describe their specific expression in immune cells and their implications in skin diseases. Although they are structurally similar and considered to be ‘cousins’, we found no common ancestor and that HPSE2 ...
Elham Vahdatahar, Clément Daviaud, Hugo Main, Rachel Havret, Claire Debarnot, Laure Favot‐Laforge, Jean‐François Jégou, Ingrid Fruitier‐Arnaudin, Antoine Dufour, Romain Vivès, Franck Morel, Yves Bourne, Kévin Baranger   +12 more
wiley   +1 more source

Assessment of Anticancer Effects of Aloe vera on 3D Liver Tumor Spheroids in a Microfluidic Platform

Biotechnology and Bioengineering, Volume 122, Issue 9, Page 2592-2608, September 2025.
The comparative effects of Doxorubicin and Aloe vera on HepG2 spheroids grown in a microfluidic device are illustrated in the graphical abstract. In the upper panel, red markers indicate that Doxorubicin treatment primarily induces necrosis in the spheroids.
Atakan Tevlek, Gunes Kibar, Barbaros Cetin   +2 more
wiley   +1 more source

Sebaceous carcinoma: clinical and demographic profile of patients in a tertiary referral hospital in Brazil. [PDF]

An Bras Dermatol
Yendo TM, Damiani FM, Matayoshi S, Nico MMS.   +3 more
europepmc   +1 more source

In Vivo Reflectance Confocal Microscopy Findings in a Case of Syringoid Eccrine Carcinoma

JEADV Clinical Practice, Volume 4, Issue 4, Page 862-866, September 2025.
Capsule Summary Herein a case of a 77‐year‐old female with a syringoid eccrine carcinoma is presented. Reflectance confocal microscopy (RCM) showed at the epidermal level multiple hyporreflective luminal spaces that extended to the dermis, some of them with an amorphous mid‐refractive material. The adjacent stroma had a dense sclerotic appearance.
J. M. Villa‐Gonzalez, R. Gamo‐Villegas, A. Pogorzelska‐Antkowiak, J. Cuevas, S. Gonzalez   +4 more
wiley   +1 more source

Stabilization of a recalcitrant and aggressive necrobiotic xanthogranuloma with tofacitinib. [PDF]

An Bras Dermatol
Mansilla-Polo M, Abril-Pérez C, Martín-Torregrosa D, Botella-Estrada R.   +3 more
europepmc   +1 more source

Chimerolectins: Classification, structural architecture, and functional perspectives

Protein Science, Volume 34, Issue 9, September 2025.
Abstract Lectins are proteins or glycoproteins capable of binding specifically and reversibly to carbohydrates, a property that, in itself, gives them great functional versatility in organisms from all kingdoms of nature. A subclass of these proteins, called chimerolectins, is composed of proteins that have at least one lectin domain associated with ...
Vanir Reis Pinto‐Junior, Benildo Sousa Cavada, Kyria Santiago Nascimento   +2 more
wiley   +1 more source

Aggressive subtypes in basal cell carcinomas might need different treatment and follow-up due to the higher risk of surgically uncontrollable recurrences. [PDF]

Graefes Arch Clin Exp Ophthalmol
Sonntag SR, Beach R, Gniesmer S, Tohme J, Grisanti S, Mohi A, Yang SH, Kakkassery V.   +7 more
europepmc   +1 more source

Battle in the Clouds

American Anthropologist, Volume 127, Issue 3, Page 594-610, September 2025.
ABSTRACT This narrative experiment brings together scenes from my family histories in western Pennsylvania coal country, alongside ongoing visits to learn about rising health issues in the region today. Increasing numbers of residents express concerns about chronic problems such as young cancers, and many people worry about potential exposures coming ...
Amy Moran‐Thomas
wiley   +1 more source

Improved Outcomes in Lower Eyelid Reconstruction With Biodegradable Implant: A Comparative Study. [PDF]

Plast Reconstr Surg Glob Open
Jonnazarov E, Cervatiuc M, Reshetov IV, Saakyan SV, Chuchueva ND.   +4 more
europepmc   +1 more source