Results 111 to 120 of about 173,176 (244)

The genomic mutation spectrums of breast fibroadenomas in Chinese population by whole exome sequencing analysis

open access: yesCancer Medicine, 2019
Fibroadenomas (FAs) are the most common fibroepithelial lesions and the most common benign tumors of the breast in women of reproductive age. Although MED12 mutations, an overwhelming majority of all mutations, and some other gene mutations have been ...
Shang‐Nao Xie   +7 more
doaj   +1 more source

A celebritização da sociedade e da cultura: entendendo a dinâmica estrutural da cultura da celebridade [PDF]

open access: yes, 2014
In recent debates about the ever-growing prominence of celebrity in society and culture, a number of scholars have started to use the often intermingled terms ‘celebrification’ and ‘celebritization’.
Driessens, Olivier
core  

Ferroptosis: The Demise of Cells Through Phospholipid Peroxidation

open access: yesAdvanced Science, EarlyView.
The relative abundance of peroxidation‐resistant monounsaturated fatty acids (MUFAs) vs. peroxidation‐sensitive polyunsaturated fatty acids (PUFAs) incorporated into phospholipid (PL) is a key determinant of ferroptosis sensitivity, as the peroxidation of PL PUFA acyl chains (PUFA‐PL) disrupts membrane integrity, causing ferroptotic cell death ...
Shaojie Cui, Jin Ye
wiley   +1 more source

EFEITOS DA COMUNIDADE DE ORIGEM NO PARTICIPANTE DE COMUNIDADES VIRTUAIS DE MARCA [PDF]

open access: yes, 2012
The question about the effectiveness of companies in maintaining their own communities versus benefiting from the ones ownedby consumers remains open. We examine differences between firm-managed and customer-managed brand communities regarding the impact
Hugo Fridolino Müller Neto   +3 more
core  

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

open access: yesAdvanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou   +8 more
wiley   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin   +7 more
wiley   +1 more source

Uma perspectiva sobre fãs ao longo da trajetória de vida*

open access: yesMatrizes, 2016
Neste artigo, abordamos os fãs sob a perspectiva da trajetória de vida, particularmente com ênfase na situação de ser um fã e o desenvolvimento da fase adulta.
C. Lee Harrington, Denise D. Bielby
doaj  

Introdução à gestão de PME (Tópico 1) [PDF]

open access: yes, 2019
Dada a importância das PME no tecido empresarial (em Portugal e na Europa), a ideia de gerir uma PME à semelhança da gestão de uma grande empresa ganha cada vez mais sentido.
Jacquinet, Marc
core  

Kenyan Farmers' Policy Priorities During Economic Crisis and Stability: Insights From a Best‐Worst Scaling Experiment

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Amid rising food and fertilizer prices, understanding farmers' policy preferences is critical for effective crisis response. We use best‐worst scaling experiment to assess Kenyan mobile‐owning crop farmers' preferences for government support under high and normal price scenarios.
Mywish K. Maredia   +4 more
wiley   +1 more source

Descobrindo a Comunidade Otaku Portuguesa: os Fãs Online

open access: yesVozes e Diálogo, 2013
O anime é uma parte integrante da cultura nipónica e cada vez mais espalhada pelo mundo, com uma vasta comunidade de okatus (fãs). Este artigo pretende interrogar de que forma a pequena comunidade em Portugal se organiza longe do público em geral e como ...
Catarina Navio, Ana Jorge
doaj  

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