Results 41 to 50 of about 37,005 (215)

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura, Tomomi Yamaguchi, Tomoki Kosho   +2 more
wiley   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland, Amber Nakar Weinstein, Eric C. Kao, Xiaonan Zhao, Monika Weisz‐Hubshman   +4 more
wiley   +1 more source

¿Son útiles la somatostatina y sus análogos (octreótido y lanreótido) en el manejo del paciente con fístula entero-cutánea?: Revisión sistemática de la literatura Are somatostatin and its analogues (octreotide and lanreotide) useful in the management of patients with enterocutaneous fistulae?: Systematic literature review

Revista Colombiana de Cirugía, 2010
Introducción. Las fístulas entero-cutáneas son una complicación infrecuente pero catastrófica para el paciente quirúrgico. En su manejo, el uso de la somatostatina y de sus análogos (octreótido/ lanreótido) se indica con frecuencia pero los resultados ...
Luis Carlos Domínguez, Álvaro Enrique Sanabria, Neil Valentín Vega, Camilo Osorio   +3 more
doaj  

A rare complication of Meckel's diverticulum: A fistula between Meckel's diverticulum and the appendix

Asian Journal of Surgery, 2012
Meckel diverticulum is the most common congenital anomaly of the small intestine, occurring in about 2%–4% of the population. Meckel diverticulum results from incomplete closure of the omphalomesenteric duct.
Ping-Fu Yang, Chau-Yun Chen, Fang-Jung Yu, Sheau-Fang Yang, Yi Ting Chen, Li-Chun Kao, Jaw-Yuan Wang   +6 more
doaj   +1 more source

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin, Lise Marty, Jérôme Drouin, Sara Miranda, Jérémie Botton, Valérie Olié, Alain Weill, Rosemary Dray‐Spira   +7 more
wiley   +1 more source

DOENÇA DE CROHN COMPLICADA POR FÍSTULA: RELATO DE CASO

Revista Uningá, 2018
RESUMO   A doença de Crohn é uma inflamação intestinal crônica que pode acometer qualquer porção do trato digestivo e pode ser complicada pela obstrução intestinal ou pela perfuração localizada com formação de fístula. Estas complicações podem ser
Rebeca Romeiro Calixto, Cynthia Neves de Vasconcelos   +1 more
doaj  

Comparative effectiveness of ustekinumab versus infliximab in the management of perianal fistulizing Crohn's disease: a retrospective study in China [PDF]

Intestinal Research
Background/Aims Ustekinumab (UST) and infliximab (IFX) are both effective in the treatment of perianal fistulizing Crohn’s disease (CD), but limited research has focused on comparing the efficacy of UST versus IFX in this field.
Mengqi Chen, Zihan Chen, Jianming Lin, Linxin Liu, Tong Tu, Xiaoling Li, Baili Chen, Yao He, Minhu Chen, Zhirong Zeng, Xiaojun Zhuang   +10 more
doaj   +1 more source

Case‐malformed signal detection and prioritisation using EUROmediCAT data for pharmacovigilance in pregnancy

British Journal of Clinical Pharmacology, EarlyView.
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson, Helen Dolk, Maria Loane, Christine Damase‐Michel, Joanne Given, Hedvig Nordeng, Jorieke E. H. Bergman, Iain Carey, Elly Den Hond, Ester Garne, Florence Rouget, Lea Bruneau, Isabelle Monier, Anke Rissmann, Mary O'Mahony, Miriam Gatt, Renée Lutke, Joanna Sichitiu, Elisa Ballardini, Alessio Coi, Clara Cavero Carbonell, David Tucker, Joan Morris   +22 more
wiley   +1 more source

Fístulas externas de intestino delgado

Cirugía del Uruguay, 1978
Dada la amplitud del tema, se estudiaron sólo las fístulas externas del intestino delgado por considerarse más importanes. Luego de definirlas y clasificarlas, y con el fin de tener una idea certera de la morbimortalidad de esta complicación en nuestro ...
Guillermo Mesa, Alberto Cid, Alberto Del Campo, Miguel Mate, Marcos Segal, José Trotschansky   +5 more
doaj  

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source