Results 191 to 200 of about 8,470,173 (241)

From productive coupling to catalytic commitment: An evolutionarily tuned interdomain connector in Leishmania Aha1 orchestrates Hsp90 activation

open access: yesThe FEBS Journal, EarlyView.
LbAha1 activates LbHsp90 through a multistep mechanism in which productive N‐domain docking precedes ATP‐driven rearrangement and linker ordering. The LbAha1 linker transitions from a flexible to helical state, stabilizing an asymmetric, catalytically competent closed complex.
Paulo Roberto Dores‐Silva   +9 more
wiley   +1 more source

Microscopy insights into reef coral fluorescent proteins: Diversity, light energy transfer and biological function

open access: yesJournal of Microscopy, EarlyView.
Abstract Fluorescent proteins (FPs) and chromoproteins (CPs) of reef‐building corals, which generate much of their vivid colouration, occupy a distinctive position at the interface of natural photonics, symbiosis biology and fluorescence microscopy.
Anya Salih
wiley   +1 more source

Sugars as Central Integrators of Plant Immunity and Stress Responses

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Sugars are fundamental metabolites that sustain plant growth and development, but accumulating evidence demonstrates that they also function as regulatory hubs in plant defence. In this review, we synthesise current knowledge on how carbohydrate dynamics coordinate metabolism, signalling, and structural responses to shape plant resistance ...
Anna Wlazło   +2 more
wiley   +1 more source

A Förster Resonance Energy Transfer (FRET)-Based Immune Assay for the Detection of Microcystin-LR in Drinking Water. [PDF]

open access: yesSensors (Basel)
Capo A   +8 more
europepmc   +1 more source

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins   +23 more
wiley   +1 more source

Astrocytic EAAT‐2 Upregulation Supports Neuro‐Axonal Homeostasis in Chronic Inflammatory CNS Lesions

open access: yesGlia, Volume 74, Issue 12, December 2026.
Inflammatory CNS lesions increase extracellular glutamate. Astrocytic EAAT regulation controls glutamate clearance, stabilizes axonal Ca2+ homeostasis, and determines neurite survival during chronic neuroinflammation. ABSTRACT Neuronal loss in multiple sclerosis (MS) is a key factor in the progression of disability.
Luise Reukauf   +9 more
wiley   +1 more source

Facile Tailoring of Metal-Organic Frameworks for Förster Resonance Energy Transfer-Driven Enhancement in Perovskite Photovoltaics. [PDF]

open access: yesAdv Sci (Weinh)
Liang X   +13 more
europepmc   +1 more source

Adrenergic Contraction of Human Prostate Tissues Is Maintained Under the Rab GTPase Inhibitors Nexhinib20 and CID1067700

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT α1‐Adrenoceptors are an important drug target in benign prostatic hyperplasia (BPH) and have been intensively studied at the expression level, but their posttranslational regulation in the prostate is widely unknown. Here we examined modulation of prostate smooth muscle contractions by inhibitors for RabGTPases, which are involved in ...
Luca Troffer   +9 more
wiley   +1 more source

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