Results 281 to 290 of about 80,011 (352)
Monitoring Hierarchical Assembly of Ring-in-Ring and Russian Doll Complexes Based on Carbon Nanoring by Förster Resonance Energy Transfer. [PDF]
JACS AuGuo S +11 more
europepmc +1 more source
Small, EarlyView.Stimuli‐responsive graphically‐encoded hydrogel microparticles, termed Novabeads, achieve rapid, enzyme‐free, multiplexed detection of biomarkers at picomolar sensitivity (LOD = 28.8 pM). Leveraging pH‐responsive signal amplification and dense bioreceptor immobilization, Novabeads yield a 35‐fold fluorescence enhancement over standard hydrogel ...
Haoliang Lu +3 more
wiley +1 more source
Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections
Small Science, EarlyView.This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton +3 more
wiley +1 more source
Improvement of the Green-Red Förster Resonance Energy Transfer-Based Ca2+ Indicator by Using the Green Fluorescent Protein, Gamillus, with a Trans Chromophore as the Donor. [PDF]
ACS SensMatsuda T, Sakai S, Okazaki KI, Nagai T.
europepmc +1 more source
Small Methods, EarlyView.Single‐molecule fluorescence detection can become highly challenging for diluted concentrations in the picomolar range. This “low concentration barrier” is broken into and achieves quantitative detection down to 0.1 pM. Introducing a diaphragm into a standard confocal microscope and implementing fluorescence lifetime correlation spectroscopy (FLCS ...
Malavika Kayyil Veedu, Jérôme Wenger
wiley +1 more source
Small Methods, EarlyView.A small‐circle scanning fluorescence correlation spectroscopy (sFCS) technique is presented using acousto‐optical laser scanning and frequency‐domain fitting. Validated with simulations and experiments, sFCS investigates cationic polyelectrolyte adsorption onto anionic nanoparticles, revealing stable complexes and size increases with polymer mass ...
Lucas Oorlynck +9 more
wiley +1 more source
Quantification of Azides on the Surface of Nanoparticles: Toward Precise Bioconjugation
Small Structures, EarlyView.Herein, two spectroscopic methods for surface azides quantification are developed. The first method is based on the ability of electron‐withdrawing ligands to quench the fluorescence of conjugated dyes, whereas the second method is more general and is based on the UV–Vis monitoring of alkyne absorbance during the click reaction.
Elizaveta Maksimova +2 more
wiley +1 more source
Head‐to‐head comparison between ACQ and FRET in probing polymeric micelles
VIEW, EarlyView.Medical nanocarriers promise precise drug delivery but are hard to monitor because common fluorescent tags often give misleading signals in complex biological systems. In our study, we directly compared two labeling strategies—an aggregation‐caused quenching (ACQ) probe (FD‐B21) and a Förster resonance energy transfer (FRET) pair (DiD/DiR)—to track ...
Runtong Zhang +9 more
wiley +1 more source