Results 41 to 50 of about 16,694 (193)

A protein L-based immunodiagnostic approach utilizing time-resolved Förster resonance energy transfer. [PDF]

PLoS ONE, 2014
Chelated lanthanides such as europium (Eu) have uniquely long fluorescence emission half-lives permitting their use in time-resolved fluorescence (TRF) assays.
Satu Hepojoki, Visa Nurmi, Antti Vaheri, Klaus Hedman, Olli Vapalahti, Jussi Hepojoki   +5 more
doaj   +1 more source

Managing Charge Transport and Exciton Generation for Highly Efficient, Bright, and Stable Near‐Infrared Organic Radical Light‐Emitting Diodes

Advanced Functional Materials, EarlyView.
High‐performing near‐infrared (NIR) organic light‐emitting diodes are demonstrated using an efficient and stable 800 nm‐emissive organic radical and a thermally activated delayed fluorescence (TADF) host. TADF‐assisted exciton generation combined with improved charge transport enables high external quantum efficiency (>8%), high radiance (>70,000 mW sr−
Hwan‐Hee Cho, Min‐Hsuan Chang, Yi‐Syun Chen, Tetsuro Kusamoto, Emrys W. Evans, Yuh‐Renn Wu, Richard H. Friend   +6 more
wiley   +1 more source

Förster resonance energy transfer measurements of ryanodine receptor type 1 structure using a novel site-specific labeling method. [PDF]

PLoS ONE, 2009
While the static structure of the intracellular Ca(2+) release channel, the ryanodine receptor type 1 (RyR1) has been determined using cryo electron microscopy, relatively little is known concerning changes in RyR1 structure that accompany channel gating.
James D Fessenden
doaj   +1 more source

Protocol for deriving proximity, affinity, and stoichiometry of protein interactions using image-based quantitative two-hybrid FRET

STAR Protocols, 2023
Summary: Two-hybrid Förster resonance energy transfer (FRET) provides proximity, affinity, and stoichiometry information in binding interactions. We present an image-based approach that surpasses traditional two-hybrid FRET assays in precision and ...
Colin Feldmann, Michael Schänzler, Manu Ben-Johny, Christian Wahl-Schott   +3 more
doaj   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

Evaluating Quantum Dot Performance in Homogeneous FRET Immunoassays for Prostate Specific Antigen

Sensors, 2016
The integration of semiconductor quantum dots (QDs) into homogeneous Förster resonance energy transfer (FRET) immunoassay kits for clinical diagnostics can provide significant advantages concerning multiplexing and sensitivity.
Shashi Bhuckory, Olivier Lefebvre, Xue Qiu, Karl David Wegner, Niko Hildebrandt   +4 more
doaj   +1 more source

FRET Based Biosensor: Principle Applications Recent Advances and Challenges

Diagnostics, 2023
Förster resonance energy transfer (FRET)-based biosensors are being fabricated for specific detection of biomolecules or changes in the microenvironment.
Awadhesh Kumar Verma, Ashab Noumani, Amit K. Yadav, Pratima R. Solanki   +3 more
doaj   +1 more source

Engineering Intraframework Energy Transfer in Metal‐Organic Frameworks for Luminescent Discrimination of Bisphenol Pollutants

Advanced Functional Materials, EarlyView.
A family of isostructural lanthanide metal–organic frameworks serves as a model platform to disentangle metal‐to‐metal and linker‐to‐linker energy transfer during luminescence sensing. The results reveal that rigid lanthanide energy migration governs sensing performance, whereas linker‐mediated pathways exert only minor effects, providing mechanistic ...
Zongsu Han, Jiatong Huo, Joshua Rushlow, Zhaoyi Liu, Hong‐Cai Zhou   +4 more
wiley   +1 more source

Förster Resonance Energy Transfer in Metal Halide Perovskite: Current Status and Future Prospects

ChemistryOpen
Förster Resonance Energy Transfer (FRET) is a non‐radiative energy transfer process in a donor‐acceptor system and has applications in various fields, such as single‐molecule investigations, biosensor creation, and deoxyribonucleic acid (DNA) mechanics ...
Siyang Liu, Waseem Akram, Fanghao Ye, JingCheng Jin, Fangfang Niu, Shakeel Ahmed, Zhengbiao Ouyang, Shou‐Cheng Dong, Guijun Li   +8 more
doaj   +1 more source

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source