Results 81 to 90 of about 216,912 (262)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Meta learning of bounds on the Bayes classifier error

, 2015
Meta learning uses information from base learners (e.g. classifiers or estimators) as well as information about the learning problem to improve upon the performance of a single base learner.
Delouille, Veronique, Hero III, Alfred O., Moon, Kevin R.   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Inequalities for Quantum f-Divergence of Trace Class Operators in Hilbert Spaces [PDF]

, 2015
Some inequalities for quantum f-divergence of trace class operators in Hilbert spaces are obtained. It is shown that for normalised convex functions it is nonnegative.
Dragomir, Sever S
core   +1 more source

Stabilizing Training of Generative Adversarial Networks through Regularization

, 2017
Deep generative models based on Generative Adversarial Networks (GANs) have demonstrated impressive sample quality but in order to work they require a careful choice of architecture, parameter initialization, and selection of hyper-parameters.
Hofmann, Thomas, Lucchi, Aurelien, Nowozin, Sebastian, Roth, Kevin   +3 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

To remain or leave: Dispersal variation and its genetic consequences in benthic freshwater invertebrates

Ecology and Evolution, 2019
Variation in dispersal capacity may influence population genetic variation and relatedness of freshwater animals thus demonstrating how life‐history traits influence patterns and processes that in turn influence biodiversity. The majority of studies have
Paolo Ruggeri, Ellen Pasternak, Beth Okamura   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

On the f -divergence for non-additive measures

Fuzzy Sets and Systems, 2016
The f-divergence evaluates the dissimilarity between two probability distributions defined in terms of the Radon-Nikodym derivative of these two probabilities. The f-divergence generalizes the Hellinger distance and the Kullback-Leibler divergence among other divergence functions. In this paper we define an analogous function for non-additive measures.
Torra, Vicenç, Narukawa, Yasuo, Sugeno, Michio   +2 more
openaire   +3 more sources