Lacustrine Shale Pore Structure Influenced by Diabase Intrusions in the Cretaceous Taizhou Formation, Subei Basin, China. [PDF]
ACS OmegaSun B +6 more
europepmc +1 more source
Advanced Science, EarlyView.Strong‐yet‐ductile precipitation‐hardening alloys require novel microstructural complexity of precipitates in particularly at cryogenic condition, to constantly impart strain hardening of hard‐and‐brittle precipitates. The present work creates innovative structurally complex precipitates assembled with dispersed nanocores and a chemical‐heterogeneity ...
Shaohua Gao +9 more
wiley +1 more source
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Advanced Science, EarlyView.Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
GreenAid: a confidence-weighted ensemble deep learning system for real-time plant disease detection and management. [PDF]
Sci RepTalaat FM, Tawfik M, Shaban WM.
europepmc +1 more source
Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction
Advanced Science, EarlyView.We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen +3 more
wiley +1 more source
VariantMedium: sensitive and generalizable somatic point mutation calling with 3D DenseNets trained and evaluated on experimental data. [PDF]
Genome MedMuslu Ö +13 more
europepmc +1 more source
Advanced Science, EarlyView.This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley +1 more source
Harmonized Dual Deep Learning Architectures for Image-Based Diagnostics of Skin Neglected Tropical Diseases: Benchmark Study via Novel Funnel Framework. [PDF]
JMIR DermatolMinyilu Y, Yimer MA, Meshesha M.
europepmc +1 more source
Advanced Science, EarlyView.PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang +10 more
wiley +1 more source
Transgenerational Epigenetic Effect of Cryopreservation of F0 Rooster Sperm (<i>Gallus gallus domesticus</i>) on microRNA-Regulation and Histological Parameters of the Reproductive System of F1 Offspring. [PDF]
Animals (Basel)Ivershina A +6 more
europepmc +1 more source